Platelet-Derived Bio-Products: Classification Update, Applications, Concerns, and New Perspectives

    December 2019 in “ Transfusion and Apheresis Science ”
    Andrea Acebes-Huerta, Tamara Arias-Fernández, Ángel Bernardo, María Carmen Muñoz‐Turrillas, Judit Fernández-Fuertes, Jerard Seghatchian, Laura Gutiérrez
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    TLDR Platelet-derived bio-products help in wound healing and tissue regeneration but lack standardized methods, and their use in medicine is growing.
    In 2020, the study "Platelet-derived bio-products: Classification update, applications, concerns and new perspectives" investigated the use of platelet-derived bio-products in tissue regeneration across various clinical areas. The study found that platelets contain growth factors and other elements that aid in wound healing and tissue regeneration. These bio-products were used in several medical fields, including dermatology and ophthalmology, and to treat conditions such as ulcers and androgenetic alopecia. However, the lack of standardization in preparation and application methods made it challenging to compare clinical results. The study also proposed a comprehensive classification system for platelet-rich plasma (PRP) products, considering factors like sample collection conditions and platelet count. The document also discussed the potential of platelets as carriers for drug delivery, particularly in cancer treatment, and the use of platelet-derived microparticles in regenerative medicine. Despite some skepticism, the use of platelet-derived bio-products in clinical use was expanding.
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