Study of Platelet-Rich Plasma Application for Skin and Plastic Surgery in Recent 20 Years: A Bibliometric Analysis

February 2023 in “ Journal of cosmetic dermatology ”

Xianhui Li, Junqing Gao, Haishan Zheng, Chengyou Zou, Zhuoan Yu, Zouping Wu, Jiasheng Zhang

platelet-rich plasma PRP facial rejuvenation scar management alopecia skin tissue repair

TLDR PRP use in skin care and plastic surgery is growing, especially in the U.S. and Italy.

This bibliometric analysis of 1,931 articles on platelet-rich plasma (PRP) applications in skin and plastic surgery from 2001 to 2021 highlights a significant increase in publications, with the US, Italy, and China as top contributors. PRP has shown promise in wound healing, collagen synthesis, and hair follicle regeneration, particularly in facial rejuvenation, scar treatment, and alopecia. Despite its potential, the study emphasizes the need for standardized PRP preparation methods and dosages. Future research directions include micro-innovative PRP preparations, optimal dosing, and integration with new technologies like stem cells and 3D printing. The study underscores the necessity for more high-quality trials to validate PRP's clinical effectiveness.

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Research cited in this study

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research Platelet-Rich Plasma with Microneedling in Androgenetic Alopecia: Study of Efficacy of the Treatment and the Number of Sessions Required

1 citations, September 2021 in “PubMed”

Four PRP with microneedling sessions effectively treat androgenetic alopecia.

Systematic Review: Adipose-Derived Mesenchymal Stem Cells, Platelet-Rich Plasma, and Biomaterials as New Regenerative Strategies in Chronic Skin Wounds and Soft Tissue Defects

research Systematic Review: Adipose-Derived Mesenchymal Stem Cells, Platelet-Rich Plasma, and Biomaterials as New Regenerative Strategies in Chronic Skin Wounds and Soft Tissue Defects

70 citations, February 2021 in “International Journal of Molecular Sciences”

Fat-derived stem cells, platelet-rich plasma, and biomaterials show promise for healing chronic skin wounds and improving soft tissue with few side effects.

Injectable Platelet-Rich Fibrin: The Newest Biomaterial and Its Use in Various Dermatological Conditions in Our Practice: A Case Series

research Injectable Platelet-Rich Fibrin: The Newest Biomaterial and Its Use in Various Dermatological Conditions in Our Practice: A Case Series

23 citations, September 2020 in “Journal of Cosmetic Dermatology”

Injectable Platelet-Rich Fibrin (I-PRF) showed positive results for treating hair loss, skin texture, wrinkles, and wounds.

A Randomized Blinded Retrospective Study: The Combined Use of Micro-Needling Technique, Low-Level Laser Therapy, and Autologous Non-Activated Platelet-Rich Plasma Improves Hair Re-Growth in Patients with Androgenic Alopecia

research A Randomized Blinded Retrospective Study: The Combined Use of Micro-Needling Technique, Low-Level Laser Therapy, and Autologous Non-Activated Platelet-Rich Plasma Improves Hair Re-Growth in Patients with Androgenic Alopecia

20 citations, July 2020 in “Expert Opinion on Biological Therapy”

Using micro-needling, low-level laser therapy, and platelet-rich plasma together significantly improves hair growth in people with hair loss.

research Evaluation of Platelet-Rich Plasma as a Treatment for Androgenetic Alopecia: A Randomized Controlled Trial

33 citations, July 2020 in “Journal of The American Academy of Dermatology”

PRP treatment improves hair density and thickness for alopecia, but needs more research.

research Autologous Activated Platelet-Rich Plasma (AA-PRP) and Non-Activated (A-PRP) in Hair Growth: A Retrospective, Blinded, Randomized Evaluation in Androgenetic Alopecia

44 citations, February 2020 in “Expert Opinion on Biological Therapy”

PRP, especially AA-PRP, can help improve hair growth in androgenetic alopecia.

Impact of Different Preparation Methods to Obtain Autologous Non-Activated Platelet-Rich Plasma and Activated Platelet-Rich Plasma in Plastic Surgery: Wound Healing and Hair Regrowth Evaluation

research Impact of Different Preparation Methods to Obtain Autologous Non-Activated Platelet-Rich Plasma and Activated Platelet-Rich Plasma in Plastic Surgery: Wound Healing and Hair Regrowth Evaluation

58 citations, January 2020 in “International Journal of Molecular Sciences”

Different methods of preparing Platelet-Rich Plasma (PRP) can affect wound healing and hair regrowth in plastic surgery. Using a kit with specific standards helps isolate PRP that meets quality criteria. Non-Activated PRP and Activated PRP have varying effects depending on the tissue and condition treated. For hair regrowth, Non-Activated PRP increased hair density more than Activated PRP. Both treatments improved various aspects of scalp health.

research Comparison of Efficacy of Platelet-Rich Plasma Therapy With or Without Topical 5% Minoxidil in Male-Type Baldness: A Randomized, Double-Blind Placebo Control Trial

26 citations, December 2019 in “Indian Journal of Dermatology, Venereology and Leprology”

PRP combined with minoxidil is the most effective and safe treatment for male pattern baldness.

A Randomized, Controlled Pilot Trial Comparing Platelet-Rich Plasma to Topical Minoxidil Foam for Treatment of Androgenic Alopecia in Women

research A Randomized, Controlled Pilot Trial Comparing Platelet-Rich Plasma to Topical Minoxidil Foam for Treatment of Androgenic Alopecia in Women

22 citations, October 2019 in “Dermatologic Surgery”

Both Platelet-Rich Plasma and Minoxidil foam increase hair count in women with hair loss, but Minoxidil is more effective. However, women were more satisfied with Platelet-Rich Plasma treatment.

research Opening New Horizons in Regenerative Dermatology Using Platelet-Based Autologous Therapies

20 citations, February 2017 in “International Journal of Dermatology”

Platelet-based therapies using a patient's own blood show promise for skin and hair regeneration but require more research for confirmation.

research The Effect of Platelet-Rich Plasma in Hair Regrowth: A Randomized Placebo-Controlled Trial

214 citations, September 2015 in “Stem Cells Translational Medicine”

Platelet-rich plasma injections significantly improved hair regrowth and thickness in patients with hair loss.

research Autologous Platelet-Rich Plasma: A Potential Therapeutic Tool for Promoting Hair Growth

270 citations, March 2012 in “Dermatologic Surgery”

Platelet-rich plasma can potentially promote hair growth by stimulating cell growth and increasing certain proteins.

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Evidence-based treatments for androgenic alopecia, such as minoxidil, finasteride, low-level laser light therapy, dutasteride, platelet-rich plasma, and topical ketoconazole. It discusses the efficacy, safety, and mechanism of action of these treatments, as well as future developments in understanding this polygenic condition.

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A user diagnosed with AGA is seeking advice on hair loss treatments, comparing topical Minoxidil, Spironolactone, and Finasteride to oral medications and natural methods like dermastamping, PRP, and LED light. They are concerned about side effects and effectiveness, especially given their existing fatigue.

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community Do Platelet-rich plasma, PRP work?

in Research/Science 14 upvotes 1 year ago

Someone's brother tried Platelet-rich plasma (PRP) for hair loss; it had minimal effect on hair but improved skin appearance. Microneedling at home was suggested as a more sustainable alternative.

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Platelet-rich plasma (PRP) therapy for hair loss is expensive, painful, and often ineffective, with mixed reviews on its benefits. Alternatives like minoxidil, finasteride, and hair transplants are suggested as more reliable options.

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