TLDR The document concludes that freeze-dried platelet-rich plasma shows promise for medical use but requires standardization and further research.
The document reviews the potential and challenges of freeze-dried platelet-rich plasma (FD-PRP) in medical applications, emphasizing the need for standardization. It covers the use of FD-PRP in skin research, wound healing, musculoskeletal conditions, dentistry, and alopecia treatment. The review indicates that FD-PRP maintains biological activity and can be combined with biomaterials for advanced wound dressings and controlled growth factor release. It also compares favorably to fresh PRP in various applications, including bone regeneration and musculoskeletal research. The document suggests that FD-PRP could become a standardized off-the-shelf product, but notes the need for further research, optimization of freeze-drying procedures, and regulatory compliance. Safety concerns are addressed through donor testing and sterilization methods. The review was supported by the Basque Industry Department and the Basque Health Department, with no conflicts of interest declared by the authors.
15 citations,
May 2020 in “Journal of Dermatological Treatment” PRP treatment increases hair density and thickness in androgenetic alopecia by 79%.
22 citations,
October 2019 in “Dermatologic Surgery” Both Platelet-Rich Plasma and Minoxidil foam increase hair count in women with hair loss, but Minoxidil is more effective. However, women were more satisfied with Platelet-Rich Plasma treatment.
7 citations,
December 2016 in “Journal of The Taiwan Institute of Chemical Engineers” Pig blood plasma can be used to promote human hair growth and is a good alternative to the commonly used serum additive.
February 2023 in “Journal of Advanced Research” A new method using Platelet-rich Plasma (PRP) in a microneedle can promote hair regrowth more efficiently and is painless, minimally invasive, and affordable.
1160 citations,
November 2018 in “Physiological Reviews” The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.
June 2024 in “Frontiers in pharmacology” 2-deoxy-D-ribose gel may help regrow hair in cases of hair loss.
3 citations,
February 2023 in “International Journal of Molecular Sciences” Autologous Platelet and Extracellular Vesicle-Rich Plasma (PVRP) has potential in enhancing tissue regeneration and improving hair conditions, but its effectiveness varies due to individual differences.
November 2024 in “Plants” Et-BB3-CMU rice bran extract may be a promising natural option for promoting hair growth and preventing hair loss.
