Thyrotropin-Releasing Hormone Promotes Wound Re-Epithelialisation in Frog and Human Skin

September 2013 in “ PLOS ONE ”

Natalia Meier, Iain S. Haslam, David M. Pattwell, Guo You Zhang, Vladimir U. Emelianov, Roberto Paredes, Sebastian Debus, Debabrata Bandyopadhyay, Wolfgang Funk, Enrique Amaya, Jennifer E. Kloepper, Matthew J. Hardman, Ralf Paus

Thyrotropin-Releasing Hormone TRH wound healing keratinocyte proliferation neo-epidermis re-epithelialisation cytokeratin 6 CK6

Studysummary This study identified thyrotropin-releasing hormone (TRH) as a stimulant of wound healing in both frog and human skin models, suggesting it as a potential neuroendocrine wound repair promoter.

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