Exploring the Thyroid-Skin Connection: Concepts, Questions, and Clinical Relevance

    December 2009 in “ Journal of Investigative Dermatology ”
    Ralf Paus
    Studysummary This review explores the complex relationship between thyroid hormones and skin, discussing potential mechanisms and known interactions but reports no new clinical results, emphasizing the need for further research.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 9

    1. Endocrine Controls of Keratin Expression BioEssays · 2009
    2. Human Female Hair Follicles Are a Direct, Nonclassical Target for Thyroid-Stimulating Hormone Journal of Investigative Dermatology · 2008
    3. Thyroid Hormones Directly Alter Human Hair Follicle Functions: Anagen Prolongation and Stimulation of Both Hair Matrix Keratinocyte Proliferation and Hair Pigmentation The Journal of Clinical Endocrinology & Metabolism · 2008
    4. Maintenance of Hair Follicle Immune Privilege Is Linked to Prevention of NK Cell Attack Journal of Investigative Dermatology · 2007
    5. Topical Thyroid Hormone Accelerates Wound Healing in Mice Endocrinology · 2005
    6. Human Hair Follicles Display a Functional Equivalent of the Hypothalamic-Pituitary-Adrenal (HPA) Axis and Synthesize Cortisol The FASEB Journal · 2005
    7. Expression of Hypothalamic-Pituitary-Thyroid Axis Related Genes in Human Skin Journal of Investigative Dermatology · 2002
    8. Thyroid Hormone Receptor β1 Is Expressed in the Human Hair Follicle British journal of dermatology/British journal of dermatology, Supplement · 2000
    9. Hair Growth Inhibition by Heparin in Mice: A Model System for Studying the Modulation of Epithelial Cell Growth by Glycosaminoglycans British Journal of Dermatology · 1991