Endocrine Controls of Keratin Expression

    March 2009 in “ BioEssays
    Yuval Ramot, Ralf Paus, Stephan Tiede, Abraham Zlotogorski
    TLDR Hormones control keratin production in skin and hair.
    The review article discussed the critical role of endocrine controls in the expression of keratins, which are essential intermediate filaments in skin physiology. It highlighted that keratin gene and protein expression in mammalian skin are tightly regulated by various hormones, including thyroid hormones, glucocorticoids, retinoic acid, vitamin D, and neuroendocrine mediators. Understanding these endocrine controls is crucial for gaining insights into normal skin and hair function and could lead to new therapeutic approaches for various skin and hair diseases.
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