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GlossaryHeat Shock Protein 27 (HSP27)

small protein that helps protect cells from stress

Heat Shock Protein 27 (HSP27), also known as HSPB1, is a small protein that helps protect cells from stress by preventing the aggregation of damaged proteins and assisting in their proper folding. It plays a crucial role in cellular responses to heat shock, oxidative stress, and other environmental stressors, and is also involved in processes like apoptosis (programmed cell death) and inflammation.

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research Up-Regulation of Androgen Receptor by Heat Shock Protein 27 and miR-1 Induces Pathogenesis of Androgenic Alopecia

January 2022 in “PubMed”

Higher levels of heat shock protein 27 and lower levels of miR-1 can increase AR levels, leading to hair loss in men.

research Inflammation, Stem Cells and Wound Healing in Skin Aging

October 2022 in “Frontiers in Cell and Developmental Biology”

Aging skin is affected by inflammation, reduced stem cell function, and slower wound healing.

research Exploring the Thyroid-Skin Connection: Concepts, Questions, and Clinical Relevance

49 citations , December 2009 in “Journal of Investigative Dermatology”

Thyroid function affects skin health, with a complex interaction between the two.

research Effects of Dihydrotestosterone on Rat Dermal Papilla Cells In Vitro

19 citations , April 2015 in “European Journal of Pharmacology”

Dihydrotestosterone (DHT) doesn't affect rat skin cell growth, but it does change cell cycle, protein levels, and other cell functions, potentially shortening hair growth cycle.

research Topobiology of Human Pigmentation: P-Cadherin Selectively Stimulates Hair Follicle Melanogenesis

29 citations , January 2013 in “The journal of investigative dermatology/Journal of investigative dermatology”

P-cadherin is crucial for hair follicle pigmentation but not skin pigmentation.

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community Aronia Chokeberry and Cyanidin 3-O-arabinoside for Hair Growth (AGA) Study

in Research/Science 14 upvotes 2 years ago

A natural compound called C3A from Aronia Chokeberry can help prevent hair loss by counteracting the effects of DHT. The user has been taking 50 grams of dried organic Aronia Chokeberry daily for 30 days and will update with photos in 60 days.