Alternating Hypothyroidism and Hyperthyroidism Complicated by Thyroid Eye Disease

    October 2024 in “ Journal of the Endocrine Society
    A M Chen, Braden Barnett
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    🚨 The study primarily focuses on thyroid disorders and thyroid eye disease, which are not directly related to hair or scalp health, but thyroid function can indirectly affect hair health.
    TLDR A woman experienced fluctuating thyroid conditions and eye disease, but her symptoms improved with treatment.
    This case study describes a 70-year-old woman with a history of primary hypothyroidism who experienced alternating hypothyroidism and hyperthyroidism, a rare condition thought to be mediated by changes in thyrotropin receptor autoantibodies. Initially diagnosed with hypothyroidism in 2004, she became hyperthyroid in 2018, which was managed by adjusting her thyroid medication. Her condition was complicated by thyroid eye disease (TED), leading to severe symptoms and requiring surgical intervention. The patient returned to a stable euthyroid state on levothyroxine by 2019, and her TED symptoms improved significantly. This case highlights the potential for autoimmune hypothyroidism to convert to hyperthyroidism and underscores the need for clinician awareness and further research into this phenomenon.
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