Search

everythinglearnresearchcommunity

for

Search:↓

Type 3 5α-reductase is more common and finasteride and dutasteride strongly inhibit it.

Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

High levels of male hormones in pregnant mice cause heart enlargement and poor heart function in their female babies.

Hes1 protein is important for hair growth and regeneration, and could be a potential treatment for hair loss.

Natural herbal compounds might treat certain medical conditions by reducing DHT levels, but more research is needed to confirm their effectiveness and safety.

Thai rice bran extracts, especially from Tubtim Chumphae rice, can significantly reduce the activity of hair loss genes, with x-tocopherol showing potential as an anti-hair loss product.

All five human steroid 5α-reductase enzymes are found in the endoplasmic reticulum.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

The structure of SRD5A reveals how it reduces steroids, aiding drug design for related health conditions.

Excess androgens may cause PCOS, not just be a symptom.

Two drugs, finasteride and minoxidil, are approved for hair loss treatment, but new therapies are being developed.

Activating TSPO helps protect the retina from damage caused by high eye pressure in glaucoma.

Shallot extract may help with hair growth and treating hair loss.

Rice husk and bran extracts from the Bue Bang 3 CMU variety can potentially treat hair loss due to their antioxidant, anti-inflammatory, and anti-androgenic properties.

Asparagus racemosus root extract reduced sebum and pore size in men but not in women.

Finasteride's sexual side effects not caused by androgen deficiency or SRD5A inhibition.

DHT affects testicular development and regulates spermatogenesis in some fish.

11α-Hydroxyprogesterone is changed into different substances by certain enzymes and may play a role in prostate cancer.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Glioblastoma cells can make androgens, which might help the tumor grow.

Et-BB3-CMU rice bran extract may be a promising natural option for promoting hair growth and preventing hair loss.

BB4CMU rice bran oil may help treat hair loss and gray hair.

Compound 4 is a promising treatment for hair loss with low toxicity.

PCOS has a strong genetic basis, but more research is needed to fully understand it.

New compounds may help treat prostate cancer by reducing cell growth.

A new hair loss treatment uses tiny needles to deliver a drug-loaded lipid carrier, promoting hair growth more effectively than current treatments.

The research identified and described a gene important for hormone conversion in endangered catfish, which varies in activity during different reproductive stages and after hormone treatment.

Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.

5-alpha reductase inhibitors can cause sexual, neurologic, endocrine, and cardiovascular side effects, but these are rare and usually stop after ending treatment.

Caizhixuan hair tonic helps treat hair loss by promoting hair growth and improving hair follicles.