Cloning, Computational Analysis and Expression Profiling of Steroid 5 Alpha-Reductase 1 (SRD5A1) Gene During Reproductive Phases and Ovatide Stimulation in Endangered Catfish, Clarias Magur

    November 2023 in “ Scientific reports ”
    Deepak Agarwal, Gulshan Kumar, Mohd Ashraf Rather, Irfan Ahmad
    Studysummary This study presents the first report on cloning and characterizing the full-length cDNA of SRD5A1 in Indian catfish (Clarias magur), revealing expression differences across reproductive phases and increased expression post-Ovatide administration in ovaries and testis.
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    Research cited in this study 3

    1. Structure of Human Steroid 5α-Reductase 2 with the Anti-Androgen Drug Finasteride Nature Communications · 2020
    2. Structure of Human Steroid 5α-Reductase 2 with Anti-Androgen Drug Finasteride Research Square (Research Square) · 2020
    3. Four-Amino Acid Segment in Steroid 5 Alpha-Reductase 1 Confers Sensitivity to Finasteride, a Competitive Inhibitor Journal of Biological Chemistry · 1992