Pumpkin Seed Oil-Loaded Niosomes for Topical Application: 5α-Reductase Inhibitory, Anti-Inflammatory, and Anti-Hair Loss Effects

    July 2022 in “ Pharmaceuticals ”
    Veerawat Teeranachaideekul, Warisara Parichatikanond, Varaporn Buraphacheep Junyaprasert, Boontida Morakul
    Studysummary This study reports that pumpkin seed oil-loaded niosomes significantly decreased hair loss and increased hair growth indicators in vivo, suggesting potential as a natural anti-hair loss therapy.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 24

    1. Hair Follicle-Targeting Drug Delivery Strategies for the Management of Hair Follicle-Associated Disorders Asian Journal of Pharmaceutical Sciences · 2022
    2. Minoxidil Nanoparticles Targeting Hair Follicles Enhance Hair Growth in C57BL/6 Mice Pharmaceutics · 2022
    3. Nanostructured Drug Delivery Systems for Targeting 5-Alpha-Reductase Inhibitors to the Hair Follicle Pharmaceutics · 2022
    4. Systematic Review and Meta-Analysis of the Association Between Metabolic Syndrome and Androgenetic Alopecia Acta dermato-venereologica · 2021
    5. Effects on Steroid 5-Alpha Reductase Gene Expression of Thai Rice Bran Extracts and Molecular Dynamics Study on SRD5A2 Biology · 2021
    6. Para Rubber Seed Oil: The Safe and Efficient Bio-Material for Hair Loss Treatment Journal of cosmetic dermatology · 2020
    7. The Inflammatory Aspect of Male and Female Pattern Hair Loss Journal of Inflammation Research · 2020
    8. Post-Finasteride Syndrome: An Emerging Clinical Problem Neurobiology of Stress · 2019
    9. Caffeic Acid Skin Absorption: Delivery of Microparticles to Hair Follicles Saudi pharmaceutical journal · 2019
    10. Niosomal Delivery of Pumpkin Seed Oil: Development, Characterization, and Physical Stability Journal of Microencapsulation · 2019
    11. Quality of Life Assessment in Patients with Androgenetic Alopecia International Journal of Trichology · 2019
    12. Quantitative Analysis Using the Phototrichogram Technique of an Italian Population Suffering from Androgenic Alopecia Cosmetics · 2018
    13. Genetic and Molecular Aspects of Androgenetic Alopecia Indian Journal of Dermatology, Venereology and Leprology · 2018
    14. Adverse Sexual Effects of Treatment with Finasteride or Dutasteride for Male Androgenetic Alopecia: A Systematic Review and Meta-Analysis Acta dermato-venereologica · 2018
    15. Androgens Trigger Different Growth Responses in Genetically Identical Human Hair Follicles in Organ Culture Reflecting Their Epigenetic Diversity in Life The FASEB Journal · 2017
    16. Sexual Side Effects of 5-Alpha-Reductase Inhibitors Finasteride and Dutasteride: A Comprehensive Review Dermatology Online Journal · 2017
    17. Androgenetic Alopecia: An Update Of Treatment Options Drugs · 2016
    18. Investigation of the Plausibility of 5-Alpha-Reductase Inhibitor Syndrome Skin appendage disorders · 2016
    19. Roxithromycin-Loaded Lipid Nanoparticles for Follicular Targeting International Journal of Pharmaceutics · 2015
    20. Androgenetic Alopecia: New Insights Into the Pathogenesis and Mechanism of Hair Loss F1000Research · 2015
    21. Hair Loss and Herbs for Treatment Journal of Cosmetic Dermatology · 2013
    22. Clinical Biochemistry of Dihydrotestosterone Annals of Clinical Biochemistry · 2013
    23. The Role of Androgen and Androgen Receptor in Skin-Related Disorders Archives of Dermatological Research · 2012
    24. Standardizing the 60-Second Hair Count Archives of Dermatology · 2008

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