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GlossaryNicotinamide Adenine Dinucleotide Phosphate Hydrogen (NADPH)

coenzyme NADPH provides electrons for cellular reactions

Nicotinamide Adenine Dinucleotide Phosphate Hydrogen, commonly abbreviated as NADPH, is a coenzyme that plays a crucial role in cellular processes. It acts as a reducing agent, donating electrons and hydrogen to various biochemical reactions, which is essential for processes like fatty acid synthesis and the detoxification of reactive oxygen species.

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research CBL1-CIPK26-Mediated Phosphorylation Enhances Activity of the NADPH Oxidase RBOHC, but Is Dispensable for Root Hair Growth

32 citations , July 2018 in “FEBS letters”

A specific protein complex increases the activity of a plant enzyme, but this action is not required for plant root hair growth.

research C-Reactive Protein Promotes Adhesion of Monocytes to Endothelial Cells via NADPH Oxidase-Mediated Oxidative Stress

24 citations , January 2012 in “Journal of Cellular Biochemistry”

C-reactive protein helps monocytes stick to blood vessel cells by causing oxidative stress.

research Tanshinone, a Natural NADPH Oxidase Inhibitor, Mitigates Testosterone-Induced Hair Loss

3 citations , December 2024 in “Biomolecules & Therapeutics”

Tanshinone compounds can help prevent hair loss caused by testosterone.

research A Natural Inhibitor, 1′S-1′-Acetoxychavicol Acetate, Against Testosterone-Induced Alopecia via NADPH Oxidase Regulation

May 2025 in “Molecules”

1′S-1′-Acetoxychavicol acetate may help treat hair loss by reducing oxidative stress.

research Phenyl Propanoid 1'S-1'-Acetoxychavicol Acetate Protects Against Testosterone-Induced Alopecia by Inhibiting NADPH Oxidase

April 2025

ACA from Alpinia galanga may prevent testosterone-related hair loss.

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community A science based addition to your hair loss routine

in Research/Science 23 upvotes 1 year ago

Blocking the Mitochondrial pyruvate carrier and using aldose reductase inhibitors like Indian gooseberry and berberine may help with hair growth. Magnesium can also be added to increase NADPH.

community Bile Acid-Mediated DHT Dysregulation Hypothesis

in Research/Science 13 upvotes 1 year ago

Elevated bile acids can inhibit the enzyme AKR1C2, leading to increased DHT levels, which may accelerate hair loss in those predisposed to androgenetic alopecia. Treatments mentioned include topical minoxidil and finasteride.

community 57% increased chance of pattern hair loss independently associated with the consumption of sugary beverages in men (p<0.001) Pt 2

in Research/Science 479 upvotes 1 year ago

Sugary beverages increase the risk of pattern hair loss in men by 57%. Treatments discussed include Minoxidil, finasteride, and RU58841.

community New Research- Creatine Increasing Scalp DHT Without Corresponding Serum DHT Increase

in Research/Science 123 upvotes 1 year ago

Creatine may increase scalp DHT without affecting serum DHT, potentially speeding up male pattern baldness (MPB) for those genetically prone. Treatments mentioned include Minoxidil, finasteride, and RU58841.

community Is someone like Elon Musk still on fin and min after hair transplant?

in Transplants 2 years ago

Hair loss treatments, specifically finasteride and minoxidil, being used by wealthy individuals to combat their genetic predisposition to baldness. It also discussed other potential treatments such as RU58841 and dutasteride.

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