C-Reactive Protein Promotes Adhesion of Monocytes to Endothelial Cells via NADPH Oxidase-Mediated Oxidative Stress
January 2012
in “
Journal of Cellular Biochemistry
”
C-reactive protein CRP monocytes endothelial cells NADPH oxidase oxidative stress carotid intima-media thickness IMT lipid metabolism malondialdehyde MDA protein carbonylation monocyte chemoattractant protein-1 MCP-1 reactive oxygen species ROS inflammation-related signaling pathways atherosclerosis NOX
Studysummary This study found that C-reactive protein may enhance monocyte adhesion to endothelial cells through NOX-mediated oxidative stress, suggesting a potential mechanism for atherogenesis.
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