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GlossaryNicotinamide Adenine Dinucleotide Phosphate Hydrogen (NADPH)

coenzyme NADPH provides electrons for cellular reactions

Nicotinamide Adenine Dinucleotide Phosphate Hydrogen, commonly abbreviated as NADPH, is a coenzyme that plays a crucial role in cellular processes. It acts as a reducing agent, donating electrons and hydrogen to various biochemical reactions, which is essential for processes like fatty acid synthesis and the detoxification of reactive oxygen species.

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research CBL1-CIPK26-Mediated Phosphorylation Enhances Activity of the NADPH Oxidase RBOHC, but Is Dispensable for Root Hair Growth

32 citations, July 2018 in “FEBS letters”

A specific protein complex increases the activity of a plant enzyme, but this action is not required for plant root hair growth.

research C-Reactive Protein Promotes Adhesion of Monocytes to Endothelial Cells via NADPH Oxidase-Mediated Oxidative Stress

24 citations, January 2012 in “Journal of Cellular Biochemistry”

C-reactive protein helps monocytes stick to blood vessel cells by causing oxidative stress.

research Hypoxia Enhances the Hair Growth-Promoting Effects of Embryonic Stem Cell-Derived Mesenchymal Stem Cells Via NADPH Oxidase 4

January 2023 in “Biomedicine & Pharmacotherapy”

Low oxygen conditions improve how well certain stem cells from embryos can make hair grow longer and faster.

Mechanism-Based Inhibition of Human Steroid 5α-Reductase by Finasteride: Enzyme-Catalyzed Formation of NADP-Dihydrofinasteride, a Potent Bisubstrate Analog Inhibitor

research Mechanism-Based Inhibition of Human Steroid 5α-Reductase by Finasteride: Enzyme-Catalyzed Formation of NADP-Dihydrofinasteride, a Potent Bisubstrate Analog Inhibitor

136 citations, March 1996 in “Journal of the American Chemical Society”

Finasteride effectively blocks enzyme causing male pattern baldness.

research How Does pH Fit in with Oscillating Polar Growth?

37 citations, March 2018 in “Trends in Plant Science”

pH, calcium, and reactive oxygen species regulate plant cell growth, with key roles for NADPH oxidases and plasma membrane H+-ATPases.

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community A science based addition to your hair loss routine

in Research/Science 23 upvotes 5 months ago

Blocking the Mitochondrial pyruvate carrier and using aldose reductase inhibitors like Indian gooseberry and berberine may help with hair growth. Magnesium can also be added to increase NADPH.

community Bile Acid-Mediated DHT Dysregulation Hypothesis

in Research/Science 13 upvotes 1 month ago

Elevated bile acids can inhibit the enzyme AKR1C2, leading to increased DHT levels, which may accelerate hair loss in those predisposed to androgenetic alopecia. Treatments mentioned include topical minoxidil and finasteride.

community 57% increased chance of pattern hair loss independently associated with the consumption of sugary beverages in men (p<0.001) Pt 2

in Research/Science 485 upvotes 4 months ago

Sugary beverages increase the risk of pattern hair loss in men by 57%. Treatments discussed include Minoxidil, finasteride, and RU58841.

community New Research- Creatine Increasing Scalp DHT Without Corresponding Serum DHT Increase

in Research/Science 120 upvotes 6 months ago

Creatine may increase scalp DHT without affecting serum DHT, potentially speeding up male pattern baldness (MPB) for those genetically prone. Treatments mentioned include Minoxidil, finasteride, and RU58841.

community Is someone like Elon Musk still on fin and min after hair transplant?

in Transplants 1 year ago

Hair loss treatments, specifically finasteride and minoxidil, being used by wealthy individuals to combat their genetic predisposition to baldness. It also discussed other potential treatments such as RU58841 and dutasteride.

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