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11α-Hydroxyprogesterone is changed into different substances by certain enzymes and may play a role in prostate cancer.

DHT affects testicular development and regulates spermatogenesis in some fish.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Type 3 5α-reductase is more common and finasteride and dutasteride strongly inhibit it.

Glioblastoma cells can make androgens, which might help the tumor grow.

Natural herbal compounds might treat certain medical conditions by reducing DHT levels, but more research is needed to confirm their effectiveness and safety.

The document concludes that patient outcomes for Congenital Adrenal Hyperplasia are often not ideal because of poor management and a need for better diagnosis and treatment methods.

Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.

High levels of male hormones in pregnant mice cause heart enlargement and poor heart function in their female babies.

Thai rice bran extracts, especially from Tubtim Chumphae rice, can significantly reduce the activity of hair loss genes, with x-tocopherol showing potential as an anti-hair loss product.

New compounds may help treat prostate cancer by reducing cell growth.

Curcuma aeruginosa Roxb. may help treat hair loss by affecting specific biological pathways.

Certain HSD3B1 gene types are linked to worse prostate cancer outcomes and affect treatment response and other health conditions.

Genetic variations greatly affect individual metabolism and can impact health and disease risk.

BB4CMU rice bran oil may help treat hair loss and gray hair.

Two drugs, finasteride and minoxidil, are approved for hair loss treatment, but new therapies are being developed.

Asparagus racemosus root extract reduced sebum and pore size in men but not in women.

Et-BB3-CMU rice bran extract may be a promising natural option for promoting hair growth and preventing hair loss.

Hair RiseTM microemulsion effectively promotes hair growth and treats hair loss better than standard treatments.

Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.

Rice husk and bran extracts from the Bue Bang 3 CMU variety can potentially treat hair loss due to their antioxidant, anti-inflammatory, and anti-androgenic properties.

PCOS has a strong genetic basis, but more research is needed to fully understand it.

Finasteride's sexual side effects not caused by androgen deficiency or SRD5A inhibition.

The structure of SRD5A reveals how it reduces steroids, aiding drug design for related health conditions.

All five human steroid 5α-reductase enzymes are found in the endoplasmic reticulum.

Gene differences may affect baldness treatment response in Korean men.

The research identified and described a gene important for hormone conversion in endangered catfish, which varies in activity during different reproductive stages and after hormone treatment.

The review suggests that while many AKR1C3 inhibitors show promise for treating certain cancers, more research is needed to confirm their effectiveness in humans.

Beta-sitosterol and stigmasterol might help prevent hair loss by blocking a specific enzyme.

Compound 4 is a promising treatment for hair loss with low toxicity.