Synergistic Phytochemical and Pharmacological Actions of Hair Rise Microemulsion: A Novel Herbal Formulation for Androgenetic Alopecia and Hair Growth Stimulation

October 2024 in “ Plants ”

Anurak Muangsanguan, Warintorn Ruksiriwanich, Pichchapa Linsaenkart, Pensak Jantrawut, Pornchai Rachtanapun, Kittisak Jantanasakulwong, Sarana Rose Sommano, Korawan Sringarm, Chaiwat Arjin, Mathukorn Sainakham, Juan Manuel Castagnini

Hair RiseTM androgenetic alopecia hair growth stimulation rice bran extract shallot bulb extract licorice root extract corn kernel extract human hair follicle dermal papilla cells hair growth signaling pathways minoxidil anti-inflammatory properties antioxidant properties follicular damage 5α-reductase androgen metabolism Hair Rise AGA Rogaine

Studysummary This study reports that Hair RiseTM microemulsion, made from plant extracts, significantly enhanced hair follicle cell growth and improved hair growth signaling pathways, suggesting it as a plant-based alternative for androgenetic alopecia treatment.

Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer

The study evaluates Hair RiseTM microemulsion, a novel herbal formulation, for its effectiveness in treating androgenetic alopecia (AGA) and promoting hair growth. The formulation, which includes extracts from rice bran, shallot, licorice root, and corn kernels, enhances the proliferation of human hair follicle dermal papilla cells and activates key hair growth signaling pathways, outperforming standard treatments like minoxidil. It also exhibits strong anti-inflammatory and antioxidant properties, reduces factors contributing to follicular damage, and inhibits 5α-reductase, an enzyme involved in androgen metabolism. The microemulsion's stability and non-toxicity were confirmed, maintaining over 80% cell viability at certain concentrations. The study suggests Hair RiseTM as a promising natural alternative to synthetic AGA treatments, though further efficacy tests in AGA patients are recommended.

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