7 citations
,
May 2022 in “PLOS ONE” This study found that Hetian sheep with higher wool density produce more and finer wool, with key genes potentially influencing their wool growth and density.
2 citations
,
July 2023 in “Animals” In this study, researchers investigated a regulatory network in cashmere goat embryos and found that fibroblast growth factor 10, alongside non-coding RNAs, significantly influences hair follicle cell proliferation, offering insights into the biology of hair follicles in cashmere goats.
March 2024 in “Agriculture” The researchers reviewed the status, challenges, and future prospects of CRISPR/Cas9-mediated gene-editing technology in livestock breeding, noting its benefits and highlighting concerns about low efficiency in inserting foreign genes and off-target effects.
17 citations
,
May 2025 in “MedComm” This review highlights how organoid technology is transforming precision medicine by summarizing its development and applications in modeling diseases, testing drug efficacy, and tailoring patient-specific treatments, despite current challenges in standardization and ethical considerations.
17 citations
,
May 2021 in “Journal of Assisted Reproduction and Genetics” This study reviews the mechanisms by which SARS-CoV-2 may impact male fertility, noting potential disruptions in spermatogenesis and hormone secretion, and underscores the need for follow-up in recovered men.
27 citations
,
May 2024 in “Clinical and Translational Medicine” This review discusses the origin, characteristics, and therapeutic potential of melanocyte stem cells in skin pigmentation disorders and reports no clinical results.
8 citations
,
October 2022 in “International Journal of Molecular Sciences” This review explores the potential of self-amplifying RNA technology for protein replacement therapy in various health disorders but reports no new experimental results, indicating challenges remain for clinical approval.
July 2024 in “Journal of Investigative Dermatology” INTASYL is a promising, adaptable RNAi technology for treating skin cancers.
August 2023 in “Journal of Knowledge Learning and Science Technology ISSN 2959-6386 (online)” This review discusses the use of single-cell RNA sequencing and spatial transcriptomics to enhance understanding of the pathogenesis and targeted therapies for chronic inflammatory skin conditions, highlighting technology advancements and the need for cost reduction and standardization.
August 2024 in “Cosmetics” This review discusses genetic and pharmacogenetic insights, along with RNA interference technologies, for developing personalized therapies for androgenetic alopecia, yet presents no new clinical results.
August 2024 in “Archives of Dermatological Research” Certain genetic variants and pathways are linked to hair loss.
49 citations
,
August 2022 in “Frontiers in Immunology” This paper discusses the evolving understanding of psoriasis pathogenesis with no new clinical findings; the authors highlight the role of T-cell plasticity and regulatory cells, calling for further clinical applications using single-cell technologies.
January 2026 in “International journal of high school research” This review discusses how combining single-cell RNA sequencing and 3D bioprinting is advancing skin tissue engineering by enhancing cellular-level precision and addressing challenges like vascularization, ultimately improving regenerative outcomes and therapeutic strategies.
5 citations
,
December 2022 in “Molecular Biology” This review examines structural elements and delivery methods for nonviral DNA- and RNA-based vectors used in gene editing, but reports no new experimental results.
June 2024 in “Computational and Structural Biotechnology Journal” This review discusses the integration of omics analyses in androgenetic alopecia research, reporting no new clinical results but suggesting that collaborative multi-omics studies may enhance understanding of AGA's pathomechanisms.
10 citations
,
May 2016 in “bioRxiv (Cold Spring Harbor Laboratory)” This study observed that differences in the expression of genes related to lipid metabolism may play a major role in determining wool fiber diameter in sheep.
This study identified the combination of NCBP3, SDHA, and PTPRA as stable reference genes for normalizing gene expression in goat skin tissue research.
20 citations
,
June 2014 in “BMC genomics” This study identified the placenta at the base of the ovary as the origin of poplar seed hair development and detailed transcriptome dynamics during the growth process.
12 citations
,
February 2022 in “Gene” In this study, researchers found that the FOS gene may play a significant role in promoting hair follicle development in Tan sheep between birth and the Er-mao period.
5 citations
,
January 2021 in “Animal Production Science” In this study, 467 genes with differential expression between fine-wool and coarse-wool sheep, particularly those related to lipid metabolism, were identified as potentially influencing wool fibre diameter.
2 citations
,
November 2024 in “PeerJ” This study identified a wide range of differentially expressed lncRNAs and mRNAs in the hair follicles of Hetian sheep, which may be useful for further research on improving carpet wool quality.
December 2023 in “Animals” In this study, researchers analyzed miRNA and gene expression in the hair follicles of FMD during different hair cycle stages, identifying differential expression patterns and key pathways involved in hair follicle development and growth.
This study found that the FOS gene may play a significant role in promoting hair follicle development in Tan sheep, with elevated expression during the Er-mao period.
17 citations
,
January 2019 in “International journal of biological sciences” This study found that inserting the Tβ4 gene into cashmere goats increased cashmere yield by 74.5% without compromising quality, suggesting potential economic benefits for goat breeding.
11 citations
,
January 2018 in “Royal Society Open Science” This study investigated the formation of Type III brush hair in Chinese Haimen goats and identified genetic factors that may involve heat stress in the process.
7 citations
,
March 2018 in “Asian-Australasian journal of animal sciences” This study observed that the OCIAD2 and DCN genes in Liaoning cashmere goats have opposite effects on hair growth by interacting with the TGF-β signaling pathway, influencing follicle morphogenesis and periodic changes.
106 citations
,
March 2014 in “BioEssays” This review examines current knowledge on human epithelial hair follicle stem cells, their markers, and outlines challenges in translating findings from murine studies to human research, but does not report new experimental results.
1 citations
,
November 2014 in “Elsevier eBooks” This chapter reviews traditional and tissue-engineered treatments for skin defects and discusses advances in bioengineered skin constructs, but it presents no new experimental results.
1 citations
,
May 2023 in “Biochemical and Biophysical Research Communications” This study found that DKK1-targeting siRNA, which may activate the Wnt/β-catenin signaling pathway, showed hair growth results in mice similar to those treated with the FDA-approved minoxidil, suggesting potential as an androgenetic alopecia therapy.
January 2022 in “Figshare” This study found that knocking down lncRNA MTC in Liaoning Cashmere goat skin fibroblasts reduced cell proliferation and altered protein expression, suggesting its role in hair growth and regulatory pathways.