Skin Transcriptome Reveals the Periodic Changes in Genes Underlying Cashmere Follicle Transition in Cashmere Goats

    June 2020 in “ BMC genomics
    Feng Yang, Zhihong Liu, Meng Zhao, Qing Mu, Tianyu Che, Yingxin Xie, Lina Ma, Lu Mi, Jinquan Li, Yunlong Zhao
    TLDR The study identified key genes that regulate the growth cycle of cashmere in goats, which could help improve breeding strategies.
    The study investigated the periodic changes in gene expression associated with the transition of cashmere (ground hair) follicles in Inner Mongolian cashmere goats. By analyzing the skin transcriptome and using quantitative reverse transcription PCR, researchers identified key genes such as KAP3-1, KRTAP 8-1, and KRTAP 24-1, which showed significant fluctuations in expression throughout the year, particularly during the growth phase (March–September). These findings provided insights into the molecular mechanisms regulating hair growth and shedding, contributing to a better understanding of hair follicle biology and offering a theoretical foundation for improving cashmere production through targeted breeding strategies.
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