Integrated Analysis of Coding Genes and Non-Coding RNAs During Hair Follicle Cycle of Cashmere Goat (Capra Hircus)

    October 2017 in “ BMC Genomics ”
    Shanhe Wang, Wei Ge, Zhixin Luo, Yang Guo, Beilei Jiao, Lei Qu, Zhiying Zhang, Xin Wang
    TLDR The study improved understanding of gene roles in cashmere goat hair growth, aiding future cashmere production.
    The study on cashmere goats (Capra hircus) provided insights into the roles of coding genes, miRNAs, and lncRNAs in hair follicle development and cycling. Researchers identified 1,108 lncRNAs and 541 miRNAs during the anagen and telogen phases, with significant differential expression observed. The study highlighted the functional conservation of lncRNAs and identified miRNA-mRNA and miRNA-lncRNA interactions, constructing ceRNA networks that illustrated their roles in hair follicle biology. This research expanded the understanding of lncRNA and miRNA biology, contributing to the annotation of the goat genome and providing a foundation for future studies on improving cashmere fiber production.
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