22 citations,
July 2016 in “PLoS ONE” The study aimed to identify microRNAs (miRNAs) and genes involved in the development of hair follicles in Hu sheep, focusing on different wave patterns in lambskin. Using high-throughput sequencing, researchers found differentially expressed miRNAs and genes between small, medium, and large wave patterns. Specifically, 13, 24, and 18 miRNAs, and 54, 190, and 81 genes were differentially expressed between small and large, small and medium, and medium and large waves, respectively. These genes were involved in processes like cell differentiation and growth, and were linked to MAPK and Notch signaling pathways. The study concluded that these miRNAs and genes likely played a significant role in forming different wave patterns, providing insights into the molecular mechanisms of hair follicle development in Hu sheep.
36 citations,
October 2015 in “Cell reports” Gab1 protein is crucial for hair growth and stem cell renewal, and Mapk signaling helps maintain these processes.
8 citations,
January 2015 in “Genetics and molecular research” Researchers found four key proteins that affect the development of a specific hair type in Yangtze River Delta white goats.
61 citations,
April 2013 in “PloS one” The study found key genes and pathways involved in cashmere goat hair growth stages.
854 citations,
February 2002 in “The journal of investigative dermatology/Journal of investigative dermatology” Understanding hair follicle development can help treat hair loss, skin regeneration, and certain skin cancers.
130 citations,
January 2000 in “Nature biotechnology”
