research Developmental Mechanisms Controlling Cell Fate Evolution
The conclusion is that grasping how cells determine their roles through evolution is key, with expected progress from new research models and genome editing.
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research Modulating the Stem Cell Niche for Tissue Regeneration
Changing the environment around stem cells could help tissue repair, but it's hard to be precise and avoid side effects.
research Regulation of Somatic Cell Reprogramming Through Inducible miR-302 Expression
Increasing mir-302 turns human hair cells into stem cells by changing gene regulation and demethylation.
research Epidermal Development in Mammals: Key Regulators, Signals from Beneath, and Stem Cells
Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.
research Functional Skin Grafts: Where Biomaterials Meet Stem Cells
Advancements in creating skin grafts with biomaterials and stem cells are promising, but more research is needed for clinical application.
research Hair Follicle Signaling Networks: A Dermal Papilla–Centric Approach
The document concludes that dermal papilla cells are key for hair growth and could be used in new hair loss treatments.
research Small RNAs Loom Large During Reprogramming
MicroRNAs can reprogram cells into stem cells faster and more efficiently than traditional methods.
research Human iPS Cell-Derived Cell Aggregates Exhibited Dermal Papilla Cell Properties in In Vitro Three-Dimensional Assemblage Mimicking Hair Follicle Structures
Scientists made structures that look like human hair follicles using stem cells, which could help grow hair without using actual human tissue.
research Hair Follicle Morphogenesis During Embryogenesis, Neogenesis, and Organogenesis
The document concludes that understanding adult stem cells and their environments can help improve skin regeneration in the future.
research Feasibility of Repairing Skin Defects by VEGF165 Gene-Modified iPS-HFSCs Seeded on a 3D Printed Scaffold Containing Astragalus Polysaccharide
The new method using gene-modified stem cells and a 3D printed scaffold improved skin repair in mice.
research IPSC-Based Approach for Human Hair Follicle Regeneration
The document concludes that using stem cells to regenerate hair follicles could be a promising treatment for hair loss, but there are still challenges to overcome before it can be used clinically.
research Characterization of Ectomesenchyme as an Origin of Epidermal Stem Cells
Ectomesenchyme is a key source of skin stem cells.
research Guiding Skin Organoid Generation via Extracellular Matrix Cues and Spatially Controlled Morphogen Gradients
Scientists improved how to make skin-like structures from stem cells using special gels and a device that controls growth signals, leading to better hair and skin features.
research Sensory Reinnervation of Human Skin by Human Neural Stem Cell-Derived Peripheral Neurons Ex Vivo
Human skin can be reconnected to nerves using stem cells, which may help with skin health and healing.
research Stem Cell-Derived Motor Neurons from Spinal and Bulbar Muscular Atrophy Patients
The study suggests that motor neurons created from stem cells of patients with spinal and bulbar muscular atrophy show signs of the disease, including changes in protein levels and cell functions.
research Parkinson's Disease and Skin Disorders: Non-Iatrogenic and Iatrogenic Connections
Parkinson's disease is linked to skin disorders and skin cells help in studying the disease.
research Future Horizons in Hair Restoration
New cell-based therapies may improve hair loss treatments in the future.
research Multilayered Gel-Spotting Device for In Vitro Reconstruction of Hair Follicle-Like Microstructure
The new method can create hair follicle-like structures but not complete hair with roots and shafts, needing more improvement.
research Chitosan in Dermatology: Applications and Benefits
Chitosan is useful in skin treatments because it helps with wound healing and cell growth.
research Tissue Engineering and Regenerative Medicine: Achievements, Future, and Sustainability in Asia
Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.
research Androgenic Effects on Ventricular Repolarization
ADT, especially enzalutamide, may increase the risk of heart rhythm problems and sudden death in men.
research Strategies to Enhance Epithelial-Mesenchymal Interactions for Human Hair Follicle Bioengineering
Improving the environment and cell interactions is key for creating human hair in the lab.
research Skin Organoids: A New Human Model for Developmental and Translational Research
Skin organoids are a promising new model for studying human skin development and testing treatments.
research Organ Regeneration Based on Developmental Biology: Past and Future
Scientists have made progress in growing mini-organs and regenerating parts of the skin, with plans to treat hair loss in a future trial.
research Regenerative Medicine Strategies for Hair Growth and Regeneration: A Narrative Review of Literature
New regenerative treatments for hair loss show promise but need more research for confirmation.
research Impaired LEF1 Activation Accelerates iPSC-Derived Keratinocytes Differentiation in Hutchinson-Gilford Progeria Syndrome
Faulty LEF1 activation causes faster skin cell differentiation in premature aging syndrome.
research Trends in the Global Organoid Technology and Industry: From Organogenesis in a Dish to the Commercialization of Organoids
Organoid technology is advancing and entering commercial use, with applications in disease modeling, drug development, and personalized medicine.
research Bioengineered Skin Organoids: From Development to Applications
Scientists have improved 3D models of human skin for research and medical uses, but still face challenges in perfectly replicating real skin.
research Male Pattern Hair Loss: Can Developmental Origins Explain the Pattern?
Male pattern hair loss may be linked to the developmental origins of hair follicles.
research Regenerative Medicine Approaches for Engineering a Human Hair Follicle
New treatments for hair loss show promise, including plasma, stem cells, and hair-stimulating complexes, but more research is needed to fully understand them.