research Stem Cells, Organoids and Their Applications for Human Diseases: Special Issue of BMB Reports in 2023
Organoids created from stem cells are used to model diseases, test drugs, and develop personalized and regenerative medicine.
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research Retainability of Pluripotency and Viability of Multilineage-Differentiating Stress Enduring (Muse) Cells After Repeated Cryopreservation
Muse cells keep their special features and can become different cell types even after being frozen and thawed three times.
research Bioengineering a 3D Integumentary Organ System from iPS Cells Using an In Vivo Transplantation Model
Researchers created a fully functional, bioengineered skin system with hair from stem cells that successfully integrated when transplanted into mice.
research The Role of Stem Cells in Cutaneous Wound Healing: What Do We Really Know?
Stem cells have great potential for improving wound healing, but more research is needed to find the best types and ways to use them.
research Feasibility of Repairing Full-Thickness Skin Defects by iPSC-Derived Epithelial Stem Cells Seeded on a Human Acellular Amniotic Membrane
iPSC-derived stem cells on a special membrane can help repair full-thickness skin defects.
research Generation of iPS Cells from Human Hair Follicle Dermal Papilla Cells
Researchers made stem cells from human hair follicle cells with higher efficiency than from skin cells.
research Biomaterials and Stem Cells: Promising Tools in Tissue Engineering and Biomedical Applications
Biomaterials combined with stem cells show promise for improving tissue repair and medical treatments.
research Stem Cells in Tissue Engineering
Different stem cells have benefits and challenges for tissue repair, and more research is needed to find the best types for each use.
research Generation of iPS-Derived Model Cells for Analyses of Hair Shaft Differentiation
Researchers created a mouse cell line to study hair growth and test hair growth drugs.
research CRISPR/Cas9-Based Targeted Genome Editing for Correction of Recessive Dystrophic Epidermolysis Bullosa Using iPS Cells
The research showed that CRISPR/Cas9 can fix mutations causing a skin disease in stem cells, which then improved skin grafts in mice, but more work on safety and efficiency is needed.
research Dermal Papilla Cells: From Basic Research to Translational Applications
Dermal papilla cells can help regrow hair and are promising for hair loss treatments.
research Hair Loss Treatment Uses Stem Cells to Generate Healthy New Follicles
A new hair loss treatment is being developed using reprogrammed stem cells to grow new hair follicles.
research Building a Functional Niche for Hair Follicle Stem Cells
Deleting the CRIF1 gene in mice disrupts skin and hair formation, certain proteins affect hair growth, a new compound may improve skin and hair health, blood cell-derived stem cells can create skin-like structures, and hair follicle stem cells come from embryonic cells needing specific signals for development.
research Induced Pluripotent Stem Cell Derived Keratinocyte Differentiation from Reprogrammed Blood Cells
Blood cells turned into stem cells can become skin cells similar to normal ones, potentially helping in skin therapies.
research Generation of iPS-Derived Model Cells for the Analysis of Hair Development
Researchers created a cell model to study hair growth and test hair-growth drugs.
research Induced Pluripotent Stem Cell Approach to Hair Follicle Regeneration
iPSCs could help develop treatments for hair loss.
research Strategies to Utilize iPS Cells for Hair Follicle Regeneration and the Treatment of Hair Loss Disorders
hiPSCs can help regenerate hair follicles and treat hair loss.
research Generation of an Integration-Free Human Induced Pluripotent Stem Cell Line MUSIi010-A from Occipital Scalp Fibroblasts of a Male Patient with Androgenetic Alopecia
Scientists created MUSIi010-A, a stem cell line from a balding man's scalp, to study hair loss and develop potential treatments.
research Understanding Melanocyte Stem Cells for Disease Modeling and Regenerative Medicine Applications
Melanocyte stem cells are crucial for skin pigmentation and have potential in disease modeling and regenerative medicine.
research Activation of TLR3 Enhances Stemness and Immunomodulatory Properties of Periodontal Ligament Stem Cells
Activating TLR3 improves the healing and immune properties of periodontal ligament stem cells.
research Stem Cells and Peripheral Nerve Injury: Potential and Challenges
Stem cells show promise for nerve injury treatment, but more research is needed before human use.
research Chemicals and Stem Cells in the Promotion of Regeneration
Chemicals and stem cells combined have advanced regenerative medicine with few safety concerns, focusing on improving techniques and treatment effectiveness.
research Efficient Genome Editing Using CRISPR/Cas9 Ribonucleoprotein Approach in iPS Cells for Recessive Dystrophic Epidermolysis Bullosa
Researchers fixed gene mutations causing a skin disease in stem cells, which then improved skin grafts in mice.
research Artificial Pigmented Human Skin Created by Muse Cells
Researchers created artificial human skin using special cells, which could help treat skin conditions like albinism and vitiligo.
research Periodontal Ligament Stem Cells: Regenerative Potency in Periodontium
Periodontal ligament stem cells show promise for regrowing tissues but require more research for safe, effective use.
research PBX Homeobox 1 Enhances Hair Follicle Mesenchymal Stem Cell Proliferation and Reprogramming Through Activation of the AKT/Glycogen Synthase Kinase Signaling Pathway and Suppression of Apoptosis
PBX1 helps hair stem cells grow and change by turning on certain cell signals and preventing cell death, which may be useful for hair regrowth treatments.
research Isolation and Characterization of a Fetal-Maternal Microchimeric Stem Cell Population in Maternal Hair Follicles Long After Childbirth
Fetal-maternal stem cells in a mother's hair can help with tissue repair and regeneration long after childbirth.
research Chrysanthemum Zawadskii Extract Induces Hair Growth by Stimulating the Proliferation and Differentiation of Hair Matrix
Chrysanthemum zawadskii extract helps hair grow by stimulating hair cells.
research Recreation of a Hair Follicle Regenerative Microenvironment: Successes and Pitfalls
Hair growth environment recreated with challenges; stem cells make successful skin organoids.
research Generating Induced Pluripotent Stem Cells with a High-Efficiency, Non-Invasive Method: An Improved Way to Cultivate Keratinocytes from Plucked Hair for Reprogramming
The conclusion is that the new method makes collecting cells from plucked hair to create stem cells more efficient and less invasive.