Nestin-Expressing Stem Cells from the Hair Follicle Can Differentiate into Motor Neurons and Reduce Muscle Atrophy After Transplantation to Injured Nerves
October 2013
in “
Tissue engineering. Part A
”
TLDR Hair follicle stem cells can become motor neurons and reduce muscle loss after nerve injury.
The study demonstrated that nestin-expressing stem cells derived from hair follicles could differentiate into motor neurons and, when transplanted into injured nerves, significantly reduced muscle atrophy. Mice treated with these stem cells showed larger muscle fiber areas and better-maintained nerve fibers compared to controls. This suggested a promising therapeutic approach for nerve injuries, leveraging the regenerative capabilities of hair follicle stem cells.
