TLDR Hair follicle stem cells can become motor neurons and reduce muscle loss after nerve injury.
The study demonstrated that nestin-expressing stem cells derived from hair follicles could differentiate into motor neurons and, when transplanted into injured nerves, significantly reduced muscle atrophy. Mice treated with these stem cells showed larger muscle fiber areas and better-maintained nerve fibers compared to controls. This suggested a promising therapeutic approach for nerve injuries, leveraging the regenerative capabilities of hair follicle stem cells.
37 citations,
January 2009 in “The Journal of Dermatology” Hair follicle stem cells can turn into various cell types and help repair nerves.
1 citations,
January 2008 in “Springer eBooks” Hair follicle stem cells can turn into many cell types and may help repair nerve damage and have other medical uses.
50 citations,
February 2007 in “Expert Opinion on Biological Therapy” Hair follicle stem cells could help repair nerves and avoid ethical issues linked to embryonic stem cells.
18 citations,
October 2014 in “In vitro cellular & developmental biology. Animal” Hair follicle stem cells can become neural cells using different methods, with varying efficiency.
4 citations,
January 2016 in “Methods in molecular biology” HAP stem cells can repair nerves, grow hair follicle nerves, and become heart muscle cells, making them useful for regenerative medicine.
25 citations,
January 2015 in “World journal of stem cells” Hair follicle stem cells can become different cell types and may help treat neurodegenerative disorders.
4 citations,
January 2016 in “Methods in molecular biology” Hair follicle stem cells can become nerve cells using specific treatments.
87 citations,
July 2018 in “Biochimica et Biophysica Acta (BBA) - Molecular Cell Research” Mice studies show that Protein Phosphatase 2A is crucial for cell growth, development, and disease prevention.