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Glossary Muscle Atrophy

decrease in muscle mass and strength due to inactivity

Muscle atrophy, also known as muscle wasting, refers to the decrease in muscle mass and strength due to a variety of factors such as prolonged inactivity, aging, malnutrition, or certain medical conditions like ALS or muscular dystrophy. This condition results from an imbalance between protein synthesis and degradation within muscle tissues, leading to the shrinkage and weakening of muscle fibers.

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Research

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research Nestin-Expressing Stem Cells from the Hair Follicle Can Differentiate Into Motor Neurons and Reduce Muscle Atrophy after Transplantation to Injured Nerves

7 citations , September 2013 in “Tissue engineering. Part A”

This study suggests that nestin-expressing hair follicle stem cells, when transplanted into transgenic mice with sciatic nerve injury, can differentiate into motor neurons and reduce muscle atrophy.

The Anti-Muscle Atrophy Effects of Ishige Sinicola in LPS-Induced C2C12 Myotubes Through Antioxidant and Anti-Inflammatory Actions

research The Anti-Muscle Atrophy Effects of Ishige sinicola in LPS-Induced C2C12 Myotubes through Its Antioxidant and Anti-Inflammatory Actions

1 citations , September 2023 in “Applied sciences (Basel)”

This study found that Ishige sinicola ethanol extract and its butanol fraction can protect against lipopolysaccharide-induced muscle atrophy in C2C12 myotubes through antioxidant and anti-inflammatory activities.

Skin Physiology in Microgravity: A 3-Month Stay Aboard ISS Induces Dermal Atrophy and Affects Cutaneous Muscle and Hair Follicles Cycling in Mice

research Skin physiology in microgravity: a 3-month stay aboard ISS induces dermal atrophy and affects cutaneous muscle and hair follicles cycling in mice

48 citations , May 2015 in “NPJ microgravity”

In this study, mice exposed to prolonged space conditions demonstrated skin atrophy, altered hair follicle cycles, and significant changes in the gene expression associated with skin muscle health.

research Lambertianic Acid from Platycladus orientalis Inhibits Muscle Atrophy in Dexamethasone-Induced C2C12 Muscle Atrophy Cells

2 citations , April 2025 in “Plants”

This study found that lambertianic acid from Platycladus orientalis leaves may protect against dexamethasone-induced skeletal muscle atrophy by reducing atrophy-related proteins without affecting cell viability.

research Long-Term Superiority of Composite Versus Muscle-Only Free Flaps for Skull Coverage

14 citations , May 2004 in “Annals of Plastic Surgery”

This study found that muscle-only free flaps for skull coverage were associated with serious complications, suggesting that composite or thicker muscle flaps may reduce these risks.

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Community Join

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community My muscles & butt are disappearing on finas, and I’m only taking it because my hair was vanishing too. Help! Details below.

in Finasteride/Dutasteride 7 upvotes 5 years ago

A 39 year old female who has been taking finasteride for 1.5 months and is experiencing side effects such as muscle and butt shrinkage, and weight loss despite still having tight clothing. The user is seeking advice from those with knowledge of bodybuilding and hormones to help figure out the issue.

community induce goosebumps to reverse hairloss

in Satire 18 upvotes 1 year ago

The conversation humorously discusses inducing goosebumps to potentially reverse hair loss, with mentions of using cold therapy and muscle exercises. It also references other unconventional ideas like removing a testicle to lower DHT.

community Nandrolone Replacement Therapy

43 upvotes 3 years ago

A user discusses starting nandrolone replacement therapy to stop hair loss and improve hair health, noting its benefits over finasteride. They report halted hair loss, improved skin, increased muscle, and a calm mood after three weeks.

community Turkey is constantly pouring money into fear mongering around finasteride in order to protect its hair transplant economy

119 upvotes 5 months ago

Finasteride and minoxidil are commonly recommended by hair transplant clinics, including those in Turkey, despite some negative perceptions and concerns about side effects. The conversation highlights differing opinions on the effectiveness and safety of these treatments, with some users expressing skepticism about side effects and others emphasizing the importance of these medications for successful hair transplants.

community Adipose tissue layer and stem cells.

4 upvotes 11 months ago

Adipose fat cells and stem cells may help treat hair loss by restoring the scalp's thickness. Treatments like NanoFat injections and Botox are discussed for their potential to promote hair growth.

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