Highly Efficient Neural Differentiation of CD34-Positive Hair-Follicle-Associated Pluripotent Stem Cells Induced by Retinoic Acid and Serum-Free Medium
January 2016
in “
Methods in molecular biology
”
TLDR Hair follicle stem cells can become nerve cells using specific treatments.
The study described the process of identifying and enriching CD34-positive hair-follicle-associated pluripotent (HAP) stem cells using magnetic-activated cell sorting (MACS) and inducing their differentiation into neuronal and glial cells with defined neural-induction media. The resulting neural cell populations were characterized through reverse transcription polymerase chain reaction (RT-PCR) and immunocytochemistry assays. This research highlighted the potential of HAP stem cells as a promising autologous source for stem cell therapy, particularly in neural differentiation.
