Dissociated Skin Cells Regenerate Hair Follicles in a Microwound: The Punch Assay

    July 2018 in “ Experimental Dermatology ”
    Xue Leng, Ping Wang, Zhihong Chen … Xunwei Wu
    Studysummary In this study, researchers developed a relatively simple punch assay for regenerating hair follicles using mouse or human cells, finding efficient hair formation with mouse cells but low efficiency with human cells on reconstituted human skin.
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    Research cited in this study 7

    1. The Patch Assay Reconstitutes Mature Hair Follicles by Culture-Expanded Human Cells Regenerative Medicine · 2017
    2. Selected Disorders of Skin Appendages: Acne, Alopecia, Hyperhidrosis Medical Clinics of North America · 2015
    3. The Endocrinology of Baldness Hormones · 2014
    4. Alopecia: A Review of Laser and Light Therapies Dermatology Online Journal · 2012
    5. Sox2-Positive Dermal Papilla Cells Specify Hair Follicle Type in Mammalian Epidermis Development · 2009
    6. Isolation and Short-Term Culture of Primary Keratinocytes, Hair Follicle Populations, and Dermal Cells from Newborn Mice and Keratinocytes from Adult Mice for In Vitro Analysis and Grafting to Immunodeficient Mice Nature Protocols · 2008
    7. Organogenesis From Dissociated Cells: Generation of Mature Cycling Hair Follicles From Skin-Derived Cells Journal of Investigative Dermatology · 2005

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