Impacts of Manipulating Cell Sorting on In Vitro Hair Follicle Regeneration

    October 2022 in “ Journal of Bioscience and Bioengineering ”
    Tatsuto Kageyama, Riki Anakama, Hideru Togashi, Junji Fukuda
    Studysummary This study found that Y27632 treatment facilitated the formation of core-shell-shaped hair follicle organoids, resulting in nearly 100% efficient hair shaft sprouting in vitro.
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    Research cited in this study 8

    1. Impact of Adipose-Derived Stem Cells on Engineering Hair Follicle Germ-Like Tissue Grafts for Hair Regenerative Medicine Journal of Bioscience and Bioengineering · 2021
    2. Establishment of an Efficient Primary Culture System for Human Hair Follicle Stem Cells Using the Rho-Associated Protein Kinase Inhibitor Y-27632 Frontiers in cell and developmental biology · 2021
    3. Hair Follicle Germs Containing Vascular Endothelial Cells for Hair Regenerative Medicine Scientific Reports · 2021
    4. Effects of Platelet-Rich Plasma on In Vitro Hair Follicle Germ Preparation for Hair Regenerative Medicine Journal of Bioscience and Bioengineering · 2020
    5. PI3K/Akt Signaling Pathway Is Essential for De Novo Hair Follicle Regeneration Stem Cell Research & Therapy · 2020
    6. Spontaneous Hair Follicle Germ Formation In Vitro, Enabling The Large-Scale Production Of HFGs For Regenerative Medicine Biomaterials · 2017
    7. Self-Organization Process in Newborn Skin Organoid Formation Inspires Strategy to Restore Hair Regeneration of Adult Cells Proceedings of the National Academy of Sciences of the United States of America · 2017
    8. Fully Functional Hair Follicle Regeneration Through the Rearrangement of Stem Cells and Their Niches Nature Communications · 2012

    Related research 5

    1. Reprogramming of Three-Dimensional Microenvironments for In Vitro Hair Follicle Induction bioRxiv (Cold Spring Harbor Laboratory) · 2022
    2. Hair Follicle Regeneration In Vitro Paleontological Journal · 2016
    3. Endogenous Human Skin Equivalent Promotes In Vitro Morphogenesis of Follicle-Like Structures Biomaterials · 2016
    4. Mesenchymal–Epithelial Interactions During Hair Follicle Morphogenesis and Cycling Seminars in Cell & Developmental Biology · 2012
    5. Control of Hair Follicle Cell Fate by Underlying Mesenchyme Through a CSL–Wnt5a–FoxN1 Regulatory Axis Genes & development · 2010