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This study found that in adolescent male rats, androgens enhance inhibitory avoidance memory, possibly by interacting with androgen receptors in the amygdala and hippocampus.

This study found that hair loss in an Olmsted syndrome mouse model with a Trpv3 mutation was linked to premature keratinocyte maturation, affecting hair follicle structure and function.

In this in-vitro study, researchers identified finasteride as the most effective FDA-approved drug for expanding functional myeloid-derived suppressor cells, suggesting its potential future use in immunosuppressive therapies.

This study found that hair follicles play a significant role in regulating skin barrier function, with disruptions in the upper hair follicle affecting the epidermis, influencing processes like desquamation and sebum release, and leading to cell movement into the epidermis.

This review discusses the role of extracellular vesicles in bone regeneration and their potential as therapeutics, highlighting challenges like standardization and safety for clinical application, but it reports no new clinical results.

This review suggests that MSC-derived conditioned media hold promise in dermatology, with studies indicating enhanced therapeutic effects when used alongside treatments like laser therapy and microneedling, leading to improved dermatological outcomes.

This review summarizes recent findings on how the dysregulated PI3K/Akt/mTOR pathway contributes to immune-mediated inflammatory skin disorders and discusses the potential of natural products, synthetic compounds, and biologic agents in their treatment. However, it emphasizes the need for further research to develop effective therapies.

In this study, researchers found that disrupting EGFR signaling in mice led to increased inflammation and hair follicle damage but that inhibiting the JAK-STAT1 pathway could restore hair growth and skin function.

This study reports that actively proliferating Lgr5+ stem cells in hair follicles do not appear to drive tumor formation in experimental skin carcinogenesis.

This study found that Lgr6+ stem cells in mice are not major initiators of UV- or chemically induced skin tumors.

This study found that a 22-bp InDel polymorphism in the FGF7 gene was significantly associated with growth traits in goats, with genotypes ID and/or II linked to better growth compared to genotype DD, indicating its potential as a molecular marker in breeding programs.

This study found that WWOX deficiency in mice leads to impaired skin development, reduced epidermal thickness, and significant hypothermia due to disrupted cell proliferation and homeostasis.

This study found that the solid self-nanoemulsifying drug delivery system improved the oral bioavailability of carvedilol significantly compared to the drug alone, enhancing its solubility, dissolution, AUC, and Cmax.

This study found no significant evidence supporting the effectiveness of platelet-rich plasma injections for treating mild-to-moderate erectile dysfunction compared to placebo.

In this study on mouse preputial glands, suppressing ATG7-dependent autophagy delayed age-related changes, affected lipid metabolism, and reduced pheromone production, highlighting autophagy's roles in glandular homeostasis and cell breakdown.

This study found that 3D-cultured dermal papilla cells more accurately mimic in vivo conditions compared to 2D cultures, enhancing our understanding of molecular mechanisms in androgen-induced alopecia.

In this study, inducible whole-body Acly-knockout mice revealed that ACLY is essential for skin homeostasis, as its deficiency led to increased sebum production and skin abnormalities, indicating a vital role for cytosolic acetyl-CoA synthesis in preserving skin barrier integrity and systemic lipid regulation.

In this study, activating TRPV1 nociceptors in mice skin stimulated dormant hair follicles and promoted hair growth through a mechanism involving dermal macrophages, fibroblasts, and neuropeptides, highlighting a new role for nociceptors in tissue recovery after injury.

In this study, researchers identified Tenascin-C as a marker for touch dome keratinocytes, which maintain themselves and can develop into Merkel cells following injury, showing they share molecular traits with various epidermal keratinocytes.

This study investigated the role of autophagy in human dermal papilla cells and found that inhibiting autophagy accelerates the catagen phase by reducing Wnt/β-catenin signaling. Furthermore, adding ginsenoside Re appears to restore autophagy, suggesting potential benefits for mitigating hair loss linked to autophagy inhibition.

This study explored the mechanism of Shaoyao Gancao decoction in treating alopecia areata and found that it may be closely related to the PI3K/AKT signaling pathway.

This study found that deleting ceramide synthase 4 in skin epidermis stem cells disrupts hair follicle and skin barrier function, leading to immune responses similar to atopic dermatitis, due to imbalances in lipid composition affecting differentiation.

This study found that ginsenoside Rg4 enhanced hair-inductive properties of dermal papilla cells via the AKT/GSK3β/β-catenin pathway, suggesting its potential as a natural therapy for hair growth.

This article presents a comprehensive overview of hair microscopy techniques and their diagnostic potential for systemic and cutaneous disorders, emphasizing its usefulness in resource-limited settings and highlighting the underutilization of this non-invasive method due to lack of awareness.

This review explores molecular targets for head and neck squamous cell carcinoma and discusses potential advancements in radiopharmaceuticals for targeted radionuclide therapy, reporting no new clinical results.

This study found that injectable platelet-rich fibrin (i-PRF) enhances hair follicle regeneration in vitro by promoting human dermal papilla cell proliferation, migration, and trichogenic inductivity, with varying effects depending on concentration.

This study developed immortalized human hair follicle-derived mesenchymal-like stromal cells (iHF-MSCs) as a consistent source of therapeutic secretome, reporting their superior immunomodulatory and regenerative performance, potentially advancing cell-free therapies for inflammation and tissue repair.

In this study, researchers observed that deleting the Gpr54 gene accelerated the hair cycle and enhanced hair regeneration in mice by modifying the NAFTc3-SFRP1-Wnt signaling pathway, suggesting Gpr54 as a potential target for hair loss treatments.

This study found that diverse persistent symptoms are common three months after COVID-19, with older age and hospital diagnosis increasing the likelihood, but early reports may overestimate their prevalence.

This study adapted a method for culturing melanocytes from human hair follicles to horses, successfully creating partially melanotic equine melanocytes, potentially advancing hair follicle biology research across species.