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This review summarizes updated US prescribing information for teriflunomide in relapsing multiple sclerosis, highlighting its efficacy in reducing lesion activity and relapse rates but noting potential adverse effects such as headache and diarrhea.

In this study, researchers found that SIRT7 activates quiescent hair follicle stem cells to promote hair growth in mice by triggering the telogen-to-anagen cycle transition, with potential implications for age-related hair loss.

In this study, researchers found that Gab1 is critical in controlling the hair cycle and the self-renewal of hair follicle stem cells in mice.

This study found that overexpression of sPLA2-X in mice was associated with alopecia and hair follicle abnormalities, highlighting its potential role in hair follicle homeostasis.

This study found that human sweat glands contain unique stem cells with significant multilineage differentiation potential and self-renewal abilities, suggesting promising clinical applications due to easy biopsy access.

This study found that knocking out the transactivation domain of Miz1 in mouse keratinocytes disrupted hair follicle orientation, caused irregular pigmentation, and increased keratinocyte proliferation, indicating Miz1's role in hair follicle development and morphogenesis.

This study found that the orphan protein Plet-1 is expressed in specific keratinocytes of mouse hair follicles and may regulate keratinocyte interactions with inert tissues by affecting migration and adhesion.

This study concluded that MEX3A is critical for maintaining Lgr5+ intestinal stem cells by regulating the PPARγ pathway, impacting intestinal homeostasis during postnatal development in mice.

This review discusses the expanded understanding of WNT10B's role in various tissues and diseases over the past decade, emphasizing its genetic correlations and potential therapeutic implications, but reports no new clinical results.

This study found that mice lacking sPLA2-IIE had distinct skin abnormalities, particularly affecting hair follicles, highlighting the differing roles of sPLA2 isoforms in mouse skin.

In this study, Hedgehog signaling in dermal papilla fibroblasts was found to accelerate hair growth and induce follicle multiplication in mice via the SCUBE3/TGF-β pathway, with some effects observed in human scalp hair follicles.

This study suggests that mouse lineage specification during pre-implantation development involves distinct timing and mechanisms for trophectoderm and inner cell mass differentiation, challenging existing models.

This study found that Frizzled genes Fzd3 and Fzd6 are redundantly involved in controlling hair follicle polarity in mice, but operate through distinct mechanisms, highlighting their complex role in hair orientation.

This study demonstrated that human hair follicle stem cells can be efficiently differentiated into endothelial-like cells using VEGF and bFGF, suggesting their potential as a novel cell source for vascular tissue engineering.

The authors concluded that for women with PCOS, the COVID-19 pandemic and resulting lockdown exacerbated existing challenges, particularly impacting their mental health due to restricted healthcare access and increased uncertainty.

This study found that mice with a mutation in the Zdhhc13 gene exhibited increased susceptibility to skin cancer, highlighting a potential protective role of palmitoyl acyltransferase in skin carcinogenesis.

This study found that Foxp1, a transcriptional factor, plays a key role in regulating hair follicle stem cell proliferation by modulating oxidative stress and the cell cycle during hair growth phases.

The researchers reported that their novel formulation of pterostilbene-loaded ethoniosomes with folic acid coating effectively targeted lung cancer cells in vitro and demonstrated promising results in animal models, indicating potential for future targeted chemotherapy applications.

In this study, lifelong barley intake in SAMP8 mice was associated with extended lifespan, improved aging-related phenotypes, and beneficial shifts in the intestinal microbiome.

This study developed an efficient method for isolating and enriching multipotent ovine hair follicle stem cells, which may aid in research on the ovine hair cycle and future wool production.

This study found that a 3D co-culture of endothelial colony-forming cells and adipose-derived stem cells restored stem cell properties and improved healing in a mouse model of chronic injury.

This study found that normal human melanocytes can be protected from apoptosis through both PI 3-kinase/Akt-dependent and independent pathways, with insulin and TPA offering nearly complete protection.

This study observed that Epigallocatechin-3-gallate (EGCG) can inhibit phosphorylation of STAT1 and reduce a specific subset of immune cells in vitro and ex vivo, suggesting a potential role in maintaining immune privilege in alopecia areata.

This review summarizes existing evidence on how YAP and TAZ proteins are activated in epidermal keratinocytes and their role in coordinating with other signaling molecules to control transcription and influence epidermal cell fate, highlighting their importance beyond the Hippo pathway.

This study examined attractive white celebrities and found no significant difference in central forehead height between genders, but reported narrower and downward slanting foreheads in women, which may influence facial rejuvenation and gender-affirming surgery approaches.

In this study, researchers observed that EGFR deficiency in the epidermis affects gene expression related to cell differentiation and structure, highlighting spatial and temporal roles of EGFR during skin and hair follicle development.

This study explored the dermal stem cell niche of equine hair follicles, revealing typical fibroblast morphology and confirming the expression of standard stem cell markers comparable to other species.

This study suggests that increased Wnt signaling may cause melanocyte stem cell exhaustion, leading to hair graying in aged mice by promoting excessive differentiation of melanocytes.

This review examined genetic factors in 46, XY differences/disorders of sex development and found that whole-exome sequencing is more effective than panel sequencing for molecular diagnosis. It identified regional genetic variation and emphasized next-generation sequencing's role in detecting variants related to gonadal and androgen-related genes.