The Role of WNT10B in Physiology and Disease: A 10-Year Update

    February 2023 in “ Frontiers in Cell and Developmental Biology ”
    Rachel S. Perkins, Rishika Singh, Amy N. Abell … Gustavo A. Miranda‐Carboni
    Studysummary This review discusses the expanded understanding of WNT10B's role in various tissues and diseases over the past decade, emphasizing its genetic correlations and potential therapeutic implications, but reports no new clinical results.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 13

    1. Melatonin Regulates the Periodic Growth of Cashmere by Upregulating the Expression of Wnt10b and β-Catenin in Inner Mongolia Cashmere Goats Frontiers in genetics · 2021
    2. Dermal Adipose Tissue Secretes HGF to Promote Human Hair Growth and Pigmentation Journal of Investigative Dermatology · 2021
    3. LncRNA-599547 Contributes to the Inductive Property of Dermal Papilla Cells in Cashmere Goats Through miR-15b-5p/Wnt10b Axis Animal biotechnology · 2020
    4. LncRNA-PCAT1 Maintains Characteristics of Dermal Papilla Cells and Promotes Hair Follicle Regeneration by Regulating miR-329/Wnt10b Axis Experimental Cell Research · 2020
    5. Deciphering the Molecular Morphology of the Human Hair Cycle: Wnt Signalling During the Telogen–Anagen Transformation British Journal of Dermatology · 2019
    6. Narrowband UVB Treatment Induces Expression of WNT7B, WNT10B, and TCF7L2 in Psoriasis Skin Archives of Dermatological Research · 2019
    7. The Balance of BMP6 and WNT10B Regulates the Telogen-Anagen Transition of Hair Follicles Cell Communication and Signaling · 2019
    8. Androgens Modify Wnt Agonists/Antagonists Expression Balance in Dermal Papilla Cells Preventing Hair Follicle Stem Cell Differentiation in Androgenetic Alopecia Molecular and Cellular Endocrinology · 2016
    9. Modulating Hair Follicle Size with Wnt10b/DKK1 During Hair Regeneration Experimental Dermatology · 2014
    10. Wnt10b Promotes Differentiation of Mouse Hair Follicle Melanocytes International Journal of Medical Sciences · 2013
    11. Dermal Papilla Cells Serially Cultured with Wnt-10b Sustain Their Hair Follicle Induction Activity After Transplantation into Nude Mice Cell Transplantation · 2012
    12. 1α,25-Dihydroxyvitamin D3 Modulates the Hair-Inductive Capacity of Dermal Papilla Cells: Therapeutic Potential for Hair Regeneration Stem Cells Translational Medicine · 2012
    13. Adenovirus-Mediated Wnt10b Overexpression Induces Hair Follicle Regeneration Journal of Investigative Dermatology · 2012

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