Prediction of the Mechanism of Shaoyao Gancao Decoction in the Treatment of Alopecia Areata by Network Pharmacology and Its Preliminary Verification Study

    April 2022 in “ Evidence-based Complementary and Alternative Medicine ”
    Shuying Lv, Lei Wang, Yuhang Duan … Dingquan Yang
    Studysummary This study explored the mechanism of Shaoyao Gancao decoction in treating alopecia areata and found that it may be closely related to the PI3K/AKT signaling pathway.
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    Research cited in this study 6

    1. Benefit and Risk Profile of Tofacitinib for the Treatment of Alopecia Areata: A Systematic Review and Meta-Analysis Journal of the European Academy of Dermatology and Venereology · 2019
    2. JAK Inhibitors for Alopecia Areata: A Systematic Review and Meta-Analysis JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology · 2019
    3. Ruxolitinib for the Treatment of Severe Alopecia Areata Journal of the American Academy of Dermatology · 2018
    4. Alopecia Areata, Thyroiditis, and Vitiligo Vulgaris in a Japanese Patient with Smoldering Type Adult T-Cell Leukemia/Lymphoma The Journal of Dermatology · 2016
    5. Total Glucosides of Paeony Capsule Plus Compound Glycyrrhizin Tablets for the Treatment of Severe Alopecia Areata in Children: A Randomized Controlled Trial Evidence-based complementary and alternative medicine · 2013
    6. Delayed type hypersensitivity‐induced myeloid‐derived suppressor cells regulate autoreactive T cells European Journal of Immunology · 2011