28 citations
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May 2018 in “Scientific reports” This study found that exercise decreases the expression of 5αR1, thereby enhancing the PI3K/AKT signaling pathway in PCOS rats.
26 citations
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June 2022 in “Stem Cell Research & Therapy” This study found that Tideglusib enhances wound healing in aged rats by activating the PI3K/Akt pathway, suggesting its potential for medical and cosmetic applications targeting age-related skin changes.
22 citations
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September 2022 in “Journal of Animal Science” This study suggests that the PI3K-AKT signaling pathway may significantly influence the development of different hair types in Inner Mongolia cashmere goats.
12 citations
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April 2022 in “Journal of Bioscience and Bioengineering” This study found that activating the PI3K/Akt signaling pathway in dermal papilla cells enhances their hair-inducing capabilities, suggesting potential strategies for hair regenerative medicine.
11 citations
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March 2013 in “Journal of Applied Biomedicine” This study found that β-catenin is essential for hair follicle stem cell proliferation and may regulate this process through the PI3K/Akt pathway, suggesting its potential as a therapeutic target.