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    Glossary mTOR pathway

    regulates cell growth and metabolism in response to nutrients

    The mTOR pathway, short for the mechanistic target of rapamycin pathway, is a crucial cellular signaling pathway that regulates growth, metabolism, and survival in response to nutrients, growth factors, and other environmental cues. It plays a significant role in various biological processes, including cell proliferation, protein synthesis, and autophagy, and is implicated in conditions like cancer, diabetes, and neurodegenerative diseases.

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    1. 896 Androgens activate lipogenesis through an AKT-independent mTOR pathway stimulation and a limitation of autophagy in an androgen-sensitive sebocyte cell line Journal of Investigative Dermatology · 2019
    2. 1341 Possible role of mTOR signaling pathway in radiation dermatitis Journal of Investigative Dermatology · 2023
    3. Cepharanthine Inhibits Doxorubicin-Induced Cellular Senescence by Activating Autophagy via the mTOR Signaling Pathway Discovery medicine · 2023
    4. Molecular Genetics of the PI3K-AKT-mTOR Pathway in Genodermatoses: Diagnostic Implications and Treatment Opportunities 2016 · 36 citations
    5. Differential expression of mTOR signaling pathway proteins in lichen planopilaris and frontal fibrosing alopecia Acta histochemica · 2018 · 5 citations
    6. The PI3K-Akt-mTOR and Associated Signaling Pathways as Molecular Drivers of Immune-Mediated Inflammatory Skin Diseases: Update on Therapeutic Strategy Using Natural and Synthetic Compounds Cells · 2023 · 9 citations
    7. Characterization of aberrant mTOR signaling pathway in U87MG glioblastoma cell line by quantitative phosphoproteomics 2021
    8. Stimulation by exosomes from hypoxia-preconditioned hair follicle mesenchymal stem cells facilitates mitophagy by inhibiting the PI3K/AKT/mTOR signaling pathway to alleviate ulcerative colitis Theranostics · 2024
    9. Molecular pathways involved in hair follicle tumor formation: all about mammalian target of rapamycin? Experimental Dermatology · 2009 · 18 citations
    10. Fibrous Papule of the Face, Similar to Tuberous Sclerosis Complex-Associated Angiofibroma, Shows Activation of the Mammalian Target of Rapamycin Pathway: Evidence for a Novel Therapeutic Strategy? PLoS ONE · 2014 · 12 citations
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    1. New Research- Creatine Increasing Scalp DHT Without Corresponding Serum DHT Increase Reddit · 22 May 2024

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    1. Rapamycin Immune-suppressing drug, also called sirolimus