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    Did you mean NF-κB signaling?
    Glossary NF-κB signaling

    regulates immune response, inflammation, and cell survival

    NF-κB signaling, short for Nuclear Factor kappa-light-chain-enhancer of activated B cells signaling, is a critical pathway in the body that helps regulate the immune response, inflammation, and cell survival. When activated, NF-κB proteins move into the cell nucleus and turn on specific genes that help the body respond to stress, infections, and other threats. This pathway is important in many diseases, including cancer and autoimmune disorders, because it can influence how cells grow and survive.

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    1. Eupafolin nanoparticles protect HaCaT keratinocytes from particulate matter-induced inflammation and oxidative stress International Journal of Nanomedicine · 2016 · 43 citations
    2. Long noncoding RNA and gene expression analysis of melatonin-exposed Liaoning cashmere goat fibroblasts indicating cashmere growth Naturwissenschaften · 2018 · 12 citations
    3. Activation of TLR3 Enhance Stemness and Immunomodulatory Properties of Periodontal Ligament Stem Cells (PDLSCs) Springer eBooks · 2016 · 3 citations
    4. Brg1 Governs a Positive Feedback Circuit in the Hair Follicle for Tissue Regeneration and Repair Developmental Cell · 2013 · 52 citations
    5. Polydeoxyribonucleotide (PDRN) salmon sebagai agen anti penuaan Intisari Sains Medis · 2025
    6. Dynamic Signals for Hair Follicle Development and Regeneration Stem Cells and Development · 2011 · 60 citations
    7. Jieduquyuziyin prescription alleviates SLE complicated by atherosclerosis via promoting cholesterol efflux and suppressing TLR9/MyD88 activation Journal of Ethnopharmacology · 2023 · 6 citations
    8. A new mutation resulting in the truncation of the TRAF6-interacting domain of XEDAR: a possible novel cause of hypohidrotic ectodermal dysplasia: Figure 1 Journal of Medical Genetics · 2012 · 17 citations
    9. Targeting noncanonical nuclear factor kappa B signalling in CYLD cutaneous syndrome by selective inhibition of IκB kinase alpha Strathprints: The University of Strathclyde institutional repository (University of Strathclyde) · 2026
    10. The Acne-treatment Potential of Cinnamomum Camphora Chvar. Borneol Essential Oil in Vitro and in Vivo Research Square (Research Square) · 2021
    11. A 20-year retrospective clinicopathologic study on melanoma in Singapore Journal of The American Academy of Dermatology · 2019
    12. Gata6 promotes hair follicle progenitor cell renewal by genome maintenance during proliferation The EMBO Journal · 2016 · 29 citations
    13. XEDAR activates the non-canonical NF-κB pathway Biochemical and Biophysical Research Communications · 2015 · 18 citations
    14. Down-RANKing the Threat of HSV-1: RANKL Upregulates MHC-Class-I-Restricted Anti-Viral Immunity in Herpes Simplex Virus Infection Journal of Investigative Dermatology · 2015 · 2 citations
    15. Spironolactone and XPB: An Old Drug with a New Molecular Target Biomolecules · 2020 · 18 citations
    16. β‐Sitosterol—Dietary sources and role in cancer and diabetes management Food Science & Nutrition · 2024 · 8 citations
    17. Transcriptomic characterization of Lonrf1 at the single-cell level under pathophysiological conditions The Journal of Biochemistry · 2023 · 7 citations
    18. Protective role of agomelatine via modulation of TLR4/NF-κB: NLRP3/IL-1β signaling pathways in testosterone-induced benign prostatic hyperplasia in rats Naunyn-Schmiedeberg s Archives of Pharmacology · 2025
    19. SPT6 maintains epidermal homeostasis by inhibiting an NF-κB-positive feedback loop to prevent excessive inflammation Cellular and Molecular Immunology · 2026
    20. Keratinocyte-specific ablation of the NF-κB regulatory protein A20 (TNFAIP3) reveals a role in the control of epidermal homeostasis Cell death and differentiation · 2011 · 76 citations
    21. Targeting lymphoid-derived IL-17 signaling to delay skin aging Nature Aging · 2023 · 59 citations
    22. Interplay between EDA-EDAR and WNT signalling pathways in the development of skin appendages in hypohidrotic ectodermal dysplasia Pediatria i Medycyna Rodzinna · 2025 · 1 citations
    23. Wnt and Notch signaling pathway involved in wound healing by targeting c-Myc and Hes1 separately Stem Cell Research & Therapy · 2015 · 113 citations
    24. Large Screening Identifies ACE2 Positively Correlates With NF-κB Signaling Activity and Targeting NF-κB Signaling Drugs Suppress ACE2 Levels Frontiers in Pharmacology · 2021 · 13 citations
    25. Hair Follicle Disruption Facilitates Pathogenesis to UVB-Induced Cutaneous Inflammation and Basal Cell Carcinoma Development in Ptch+/− Mice American Journal of Pathology · 2014 · 8 citations
    26. In Vivo Evaluation of<i>Eclipta alba</i>Extract as Anticancer and Multidrug Resistance Reversal Agent Nutrition and Cancer · 2014 · 9 citations
    27. Plakophilin 1 suppresses keratinocyte innate immune responses through DExD/H helicases 2026
    28. Transcriptome Dynamics Reveal Stage-Specific and Melatonin-Triggered Gene Expression Patterns During The Cashmere Growth Cycle in Capra Hircus Research Square (Research Square) · 2021
    29. Identification of potential key genes and pathways associated with the Pashmina fiber initiation using RNA-Seq and integrated bioinformatics analysis Scientific Reports · 2021 · 36 citations
    30. Keratin 17 modulates hair follicle cycling in a TN<i>Fα</i>-dependent fashion Genes & Development · 2006 · 169 citations