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    Did you mean NF-κB pathway?
    Glossary NF-κB pathway

    regulates genes involved in immune and inflammatory responses

    The NF-κB pathway, short for Nuclear Factor kappa-light-chain-enhancer of activated B cells pathway, is a critical signaling mechanism in cells that regulates the expression of genes involved in immune and inflammatory responses. When activated, it can lead to the production of proteins that help fight infections and repair tissue damage, but its chronic activation is also linked to various diseases, including cancer and autoimmune disorders.

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    1. XEDAR activates the non-canonical NF-κB pathway Biochemical and Biophysical Research Communications · 2015 · 18 citations
    2. Gata6 promotes hair follicle progenitor cell renewal by genome maintenance during proliferation The EMBO Journal · 2016 · 29 citations
    3. Involvement of DKK1 secreted from adipose‐derived stem cells in alopecia areata Cell Proliferation · 2023
    4. Eupafolin nanoparticles protect HaCaT keratinocytes from particulate matter-induced inflammation and oxidative stress International Journal of Nanomedicine · 2016 · 43 citations
    5. Polydeoxyribonucleotide (PDRN) salmon sebagai agen anti penuaan Intisari Sains Medis · 2025
    6. Jieduquyuziyin prescription alleviates SLE complicated by atherosclerosis via promoting cholesterol efflux and suppressing TLR9/MyD88 activation Journal of Ethnopharmacology · 2023 · 6 citations
    7. A new mutation resulting in the truncation of the TRAF6-interacting domain of XEDAR: a possible novel cause of hypohidrotic ectodermal dysplasia: Figure 1 Journal of Medical Genetics · 2012 · 17 citations
    8. Advanced glycation end-products inhibit mesenchymal-epidermal interaction by up-regulating proinflammatory cytokines in hair follicles European Journal of Dermatology · 2015 · 3 citations
    9. Protein Kinase C Downregulation upon Rapamycin Treatment Attenuates Neuroinflammation and Mitochondrial Disease Innovation in aging · 2020
    10. Genome-wide shifts in gene expression induced in theca-interstitial cells by inflammatory stimuli Fertility and Sterility · 2018
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