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    Did you mean NF-κB pathway?
    Glossary NF-κB pathway

    regulates genes involved in immune and inflammatory responses

    The NF-κB pathway, short for Nuclear Factor kappa-light-chain-enhancer of activated B cells pathway, is a critical signaling mechanism in cells that regulates the expression of genes involved in immune and inflammatory responses. When activated, it can lead to the production of proteins that help fight infections and repair tissue damage, but its chronic activation is also linked to various diseases, including cancer and autoimmune disorders.

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    1. XEDAR activates the non-canonical NF-κB pathway Biochemical and Biophysical Research Communications · 2015 · 18 citations
    2. Gata6 promotes hair follicle progenitor cell renewal by genome maintenance during proliferation The EMBO Journal · 2016 · 29 citations
    3. Involvement of DKK1 secreted from adipose‐derived stem cells in alopecia areata Cell Proliferation · 2023
    4. Eupafolin nanoparticles protect HaCaT keratinocytes from particulate matter-induced inflammation and oxidative stress International Journal of Nanomedicine · 2016 · 43 citations
    5. Polydeoxyribonucleotide (PDRN) salmon sebagai agen anti penuaan Intisari Sains Medis · 2025
    6. Jieduquyuziyin prescription alleviates SLE complicated by atherosclerosis via promoting cholesterol efflux and suppressing TLR9/MyD88 activation Journal of Ethnopharmacology · 2023 · 6 citations
    7. A new mutation resulting in the truncation of the TRAF6-interacting domain of XEDAR: a possible novel cause of hypohidrotic ectodermal dysplasia: Figure 1 Journal of Medical Genetics · 2012 · 17 citations
    8. Advanced glycation end-products inhibit mesenchymal-epidermal interaction by up-regulating proinflammatory cytokines in hair follicles European Journal of Dermatology · 2015 · 3 citations
    9. Protein Kinase C Downregulation upon Rapamycin Treatment Attenuates Neuroinflammation and Mitochondrial Disease Innovation in aging · 2020
    10. Genome-wide shifts in gene expression induced in theca-interstitial cells by inflammatory stimuli Fertility and Sterility · 2018
    11. Dynamic Signals for Hair Follicle Development and Regeneration Stem Cells and Development · 2011 · 60 citations
    12. Activation of TLR3 Enhance Stemness and Immunomodulatory Properties of Periodontal Ligament Stem Cells (PDLSCs) Springer eBooks · 2016 · 3 citations
    13. A 20-year retrospective clinicopathologic study on melanoma in Singapore Journal of The American Academy of Dermatology · 2019
    14. The Acne-treatment Potential of Cinnamomum Camphora Chvar. Borneol Essential Oil in Vitro and in Vivo Research Square (Research Square) · 2021
    15. Cell death in the skin Apoptosis · 2009 · 120 citations
    16. Selected Abstracts Annals of Nutrition and Metabolism · 2008
    17. 5% Minoxidil topical foam on women: Menopause and other covariates Journal of The American Academy of Dermatology · 2019
    18. Transcriptomic characterization of Lonrf1 at the single-cell level under pathophysiological conditions The Journal of Biochemistry · 2023 · 7 citations
    19. 461: THE PROFIBROGENIC ROLE OF NEUTROPHIL EXTRACELLULAR TRAPS IN STENOTIC CROHN'S DISEASE: A NEW ANTIFIBROTIC TARGET? Gastroenterology · 2022
    20. Medicinal uses, pharmacological activities, phytochemistry, and the molecular mechanisms of Punica granatum L. (pomegranate) plant extracts: A review Biomedicine & Pharmacotherapy · 2022 · 202 citations
    21. β‐Sitosterol—Dietary sources and role in cancer and diabetes management Food Science & Nutrition · 2024 · 8 citations
    22. Protective role of agomelatine via modulation of TLR4/NF-κB: NLRP3/IL-1β signaling pathways in testosterone-induced benign prostatic hyperplasia in rats Naunyn-Schmiedeberg s Archives of Pharmacology · 2025
    23. Identification of potential key genes and pathways associated with the Pashmina fiber initiation using RNA-Seq and integrated bioinformatics analysis Scientific Reports · 2021 · 36 citations
    24. Wnt and Notch signaling pathway involved in wound healing by targeting c-Myc and Hes1 separately Stem Cell Research & Therapy · 2015 · 113 citations
    25. Interplay between EDA-EDAR and WNT signalling pathways in the development of skin appendages in hypohidrotic ectodermal dysplasia Pediatria i Medycyna Rodzinna · 2025 · 1 citations
    26. Molecular pathology of skin adnexal tumours Histopathology · 2021 · 16 citations
    27. Hair Follicle Disruption Facilitates Pathogenesis to UVB-Induced Cutaneous Inflammation and Basal Cell Carcinoma Development in Ptch+/− Mice American Journal of Pathology · 2014 · 8 citations
    28. Brg1 Governs a Positive Feedback Circuit in the Hair Follicle for Tissue Regeneration and Repair Developmental Cell · 2013 · 52 citations
    29. Transcriptome Dynamics Reveal Stage-Specific and Melatonin-Triggered Gene Expression Patterns During The Cashmere Growth Cycle in Capra Hircus Research Square (Research Square) · 2021
    30. Regulatory Mechanisms of Natural Active Ingredients and Compounds on Keratinocytes and Fibroblasts in Mitigating Skin Photoaging Clinical Cosmetic and Investigational Dermatology · 2024 · 10 citations