Tannic Acid Accelerates Cutaneous Wound Healing in Rats Via Activation of the ERK 1/2 Signaling Pathways

The study from July 2019 demonstrated that tannic acid (TA) significantly promotes wound healing in rats by activating the ERK 1/2 signaling pathway. TA treatment resulted in faster wound closure, enhanced re-epithelialization, and increased hair follicle growth compared to untreated wounds. The study also found that TA reduced pro-inflammatory cytokines IL-1 and IL-6, while increasing the expression of growth factors such as bFGF, which are essential for healing. These findings suggest that TA has potential as a therapeutic agent for improving wound healing and hair follicle regeneration. The study involved 72 rats, providing a substantial sample size for the research conclusions.