Jieduquyuziyin Prescription Alleviates SLE Complicated by Atherosclerosis via Promoting Cholesterol Efflux and Suppressing TLR9/MyD88 Activation

March 2023 in “ Journal of Ethnopharmacology ”

Yuanfang He, Weiyu Tian, Miao Zhang … Juan Chen

Jieduquyuziyin prescription systemic lupus erythematosus SLE hair loss TLR9 MyD88 NF-kB cholesterol efflux ABCA1 ABCG1 SR-BI PPAR-γ inflammatory factors autoantibodies foam cell formation macrophages JP lupus TLR9/MyD88/NF-kB signaling pathway cholesterol efflux genes inflammation

Studysummary In this mouse study, researchers found that the Jieduquyuziyin prescription may lessen lupus-like symptoms and atherosclerosis by inhibiting TLR9/MyD88 signaling and promoting cholesterol efflux.

Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer ·

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