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In this mouse study, researchers found that the Jieduquyuziyin prescription may lessen lupus-like symptoms and atherosclerosis by inhibiting TLR9/MyD88 signaling and promoting cholesterol efflux.

This study reports that skin bacteria can accelerate hair follicle regeneration and improve wound healing through IL-1β signaling, by activating keratinocytes in a pathway involving IL1R/Myd88.

In this animal study, AGO (agomelatine) effectively alleviated testosterone-induced benign prostatic hyperplasia in rats by reducing oxidative stress and inflammation, indicating its potential as a therapeutic option for managing BPH through specific signaling pathways.

This study found that increasing commensal bacterial load on the skin enhances wound-induced hair follicle neogenesis in mice, mediated through IL1R-MyD88 signaling pathways.

This study found that skin microbiota, particularly in wild-type mice, promotes wound-induced hair follicle neogenesis and wound healing, highlighting the potential downsides of routine antibiotic use on skin regeneration.