TLDR Hormones affect skin aging, and treatments targeting hormonal balance may improve skin health.
The document from 2015 examines the influence of hormones on skin aging, noting that hormonal imbalances can lead to skin pathologies and that aging affects skin properties such as thickness, collagen organization, and wound healing. It discusses how hormones like estrogen and testosterone can impact skin health, with estrogen replacement shown to improve skin characteristics in postmenopausal women, and testosterone replacement potentially rejuvenating aged men's skin. The document also explores the role of growth factors like TGF-β in collagen production and wound healing, and how hormonal signals like NF-kB are associated with aging skin phenotypes. Clinical applications of hormonal modification are considered for promoting skin health during aging, but the document does not provide specific participant numbers for the referenced studies. It suggests that future skin aging treatments may benefit from advances in sequencing and stem cell biology, leading to more personalized approaches and a deeper understanding of hormonal skin regulation.
150 citations,
April 2013 in “Dermato-endocrinology” Estrogen therapy can reduce skin aging but has cancer risks.
41 citations,
March 2012 in “Clinical and Experimental Dermatology” G allele of AR Stul polymorphism linked to higher hair loss risk, especially in white people.
321 citations,
January 2012 in “Cell stem cell” TGF-β2 helps activate hair follicle stem cells by counteracting BMP signals.
21 citations,
October 2011 in “British Journal of Dermatology” Testosterone therapy helped 63% of androgen-deficient women grow scalp hair, but more research is needed.
21 citations,
August 2011 in “Clinics in Dermatology” Looking at skin can help find and treat serious diseases early.
36 citations,
September 1999 in “Toxicologic pathology” Stronger corticosteroids cause more skin damage in hairless dogs, similar to effects in humans.
1 citations,
February 2024 in “Cosmetics” Cannabidiol shows promise as an effective treatment for acne.
Different stem cells are key for hair growth and health, and understanding their regulation could help treat hair loss.
1 citations,
January 2024 in “Journal of personalized medicine” Hormonal imbalances during menopause may significantly contribute to Frontal Fibrosing Alopecia.
February 2024 in “Biomedicines” Hormones like androgens, estrogen, thyroid hormones, and stress hormones can contribute to hair loss, and treatments target these hormonal imbalances.
276 citations,
April 2003 in “Molecular endocrinology” Vitamin D is important for bones, hair, blood pressure, and breast development.
