Frontal Fibrosing Alopecia and Reproductive Health: Assessing the Role of Sex Hormones in Disease Development

    January 2024 in “ Journal of personalized medicine
    Alexandra-Maria Roman, Răzvan Petca, Mihai Cristian Dumitraşcu, Aida Petca, Alina Maria Ionescu, Florica Șandru
    TLDR Hormonal imbalances during menopause may significantly contribute to Frontal Fibrosing Alopecia.
    The review "Frontal Fibrosing Alopecia and Reproductive Health: Assessing the Role of Sex Hormones in Disease Development" explores the potential hormonal origins of Frontal Fibrosing Alopecia (FFA), a type of hair loss primarily affecting postmenopausal women. The review includes 23 original studies with a total of 2667 patients, 2572 of whom are female. The studies suggest that hormonal imbalances, particularly those related to menopause, may play a significant role in FFA's development. However, the extent and mechanisms of this relationship are still under debate. The review also highlights the potential role of lifestyle triggers, such as the use of facial sunscreen and exposure to certain organic compounds found in cosmetic products. The document concludes that FFA shows a strong correlation with fluctuations in sex hormones, particularly during menopause, and recommends thorough hormonal assessments for FFA patients. Further research is needed to fully understand these relationships and develop targeted therapeutic approaches.
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