Genotyping Of The Rs1800440 Polymorphism In CYP1B1 Gene And The Rs9258883 Polymorphism In HLA-B Gene In A Spanish Cohort Of 223 Patients With Frontal Fibrosing Alopecia

    September 2023 in “ Acta dermato-venereologica ”
    David Saceda‐Corralo, ­Daniel ­Ortega‐Quijano, Gloria Muñoz-Martín … Sergio Vañó‐Galván
    Studysummary In this study, researchers found that most patients with frontal fibrosing alopecia lacked the protective rs1800440 polymorphism in the CYP1B1 gene, suggesting its potential role in the development of this condition, while a significant number carried the rs9258883 polymorphism in HLA-B*07:02.
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    Research cited in this study 11

    1. Frontal Fibrosing Alopecia: Demographic and Clinical Characteristics of 490 Cases JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology · 2019
    2. Genome-Wide Association Study in Frontal Fibrosing Alopecia Identifies Four Susceptibility Loci Including HLA-B*07:02 Nature Communications · 2019
    3. Frontal Fibrosing Alopecia: An Update on Pathogenesis, Diagnosis, and Treatment American Journal of Clinical Dermatology · 2019
    4. Study of Human Leukocyte Antigen in 13 Cases of Familial Frontal Fibrosing Alopecia: CYP21A2 Gene p.V281L Mutation from Congenital Adrenal Hyperplasia Linked to HLA Class I Haplotype HLA-A*33:01; B*14:02; C*08:02 as a Genetic Marker Australasian Journal of Dermatology · 2019
    5. An Update of the Pathogenesis of Frontal Fibrosing Alopecia: What Does the Current Evidence Tell Us? Australasian Journal of Dermatology · 2018
    6. Frontal Fibrosing Alopecia: Reflections and Hypotheses on Etiology and Pathogenesis Experimental dermatology · 2016
    7. Case Series of Familial Frontal Fibrosing Alopecia and a Review of the Literature Journal of Cosmetic Dermatology · 2015
    8. Lichen Planopilaris Is Characterized By Immune Privilege Collapse Of The Hair Follicle's Epithelial Stem Cell Niche The Journal of Pathology · 2013
    9. Genome-Wide Association Study in Alopecia Areata Implicates Both Innate and Adaptive Immunity Nature · 2010
    10. Postmenopausal Frontal Fibrosing Alopecia: A Frontal Variant of Lichen Planopilaris Journal of the American Academy of Dermatology · 1997
    11. Postmenopausal Frontal Fibrosing Alopecia: Scarring Alopecia in a Pattern Distribution Archives of Dermatology · 1994