Frontal Fibrosing Alopecia in Men: A Multicenter Study of 39 Patients

The multicenter, observational, and retrospective study collected data from 39 male patients with Frontal fibrosing alopecia (FFA) from different Spanish hospitals. The mean age at diagnosis was 69 years, and the mean duration of FFA was 7.1 years. The study found that 74.4% of patients had beard alopecia, and 89.7% had sideburn alopecia. FFA was also found to affect the hair of the face and the rest of the body. Three patients with prostate adenocarcinoma had undergone treatment with antiandrogenic drugs before the onset of FFA, suggesting that an imbalance in sex hormone levels might play a key role in the development of FFA in men. Facial sunscreens or facial moisturizers with any sunscreen filter were reported to be frequently applied by 56.4% of the patients. The study concluded that FFA should be considered a systemic condition that does not exclusively affect the scalp. Further study is needed to better characterize hormonal levels and any potential associations and to investigate any causation between hormonal imbalances and the development of FFA.