Frontal Fibrosing Alopecia in Men: A Multicenter Study of 39 Patients

    September 2021 in “ Journal of The American Academy of Dermatology ”
    Alejandro Lobato‐Berezo, Maribel Iglesias‐Sancho, Enrique Rodríguez‐Lomba, Juan Francisco Mir-Bonafé, Virginia Velasco‐Tamariz, María Librada Porriño‐Bustamante, Ramón Grimalt, Ignasi Figueras‐Nart, Andrea Combalía, Ramón M. Pujol
    Image of study
    TLDR Most men with Frontal fibrosing alopecia also lose facial hair and the condition may be linked to hormone levels and sunscreen use.
    The multicenter, observational, and retrospective study collected data from 39 male patients with Frontal fibrosing alopecia (FFA) from different Spanish hospitals. The mean age at diagnosis was 69 years, and the mean duration of FFA was 7.1 years. The study found that 74.4% of patients had beard alopecia, and 89.7% had sideburn alopecia. FFA was also found to affect the hair of the face and the rest of the body. Three patients with prostate adenocarcinoma had undergone treatment with antiandrogenic drugs before the onset of FFA, suggesting that an imbalance in sex hormone levels might play a key role in the development of FFA in men. Facial sunscreens or facial moisturizers with any sunscreen filter were reported to be frequently applied by 56.4% of the patients. The study concluded that FFA should be considered a systemic condition that does not exclusively affect the scalp. Further study is needed to better characterize hormonal levels and any potential associations and to investigate any causation between hormonal imbalances and the development of FFA.
    Discuss this study in the Community →

    Research cited in this study

    3 / 3 results

    Related Community Posts Join

    6 / 393 results

      community Diffuse thinning is so brutal.

      in Styling  72 upvotes 1 year ago
      A 25-year-old with AGA experienced hair thinning and dandruff, stabilized with topical finasteride and minoxidil but saw minimal regrowth. They seek advice on styling and consider oral minoxidil and microneedling for denser hair.
      Diffuse hair loss and scalp biopsies

      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 4 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community 9 months on Fin - no progress , should I get on Dutasteride?

      in Chat  10 upvotes 1 month ago
      The user has been using finasteride, minoxidil, and nizoral for hair loss but hasn't seen regrowth, only maintenance. They are considering switching to dutasteride, which is believed to be more effective, but are concerned about potential side effects.

      community Testosterone and hair loss seeming irrelevance

      in Research/Science  81 upvotes 1 year ago
      The conversation is about the role of testosterone in hair loss and the effectiveness of different treatments. The conclusion is that DHT is the main culprit for hair loss, and finasteride has been proven to work long-term in maintaining and regrowing hair. Testosterone may have a minor effect, but it is not the primary cause of hair loss.

      community scarring alopecia awareness in this community

      in Chat  33 upvotes 2 years ago
      Lichen Planopilaris (LPP), a form of permanent hair loss, which can be mistaken for seborrheic dermatitis and is characterized by scalp itching, burning, redness, and dandruff. Treatment options discussed include steroidal creams, finasteride, minoxidil, and RU58841.

    Similar Research

    5 / 1000+ results