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Drug Interactions Between Common Dermatological Medications and the Oral Anti-Covid-19 Agents Nirmatrelvir-Ritonavir and Molnupiravir

research Drug interactions between common dermatological medications and the oral anti-COVID-19 agents nirmatrelvir-ritonavir and molnupiravir

5 citations , December 2022 in “Annals Academy of Medicine Singapore”

This review reports that nirmatrelvir-ritonavir has significant drug-drug interactions with many common dermatological medications, whereas molnupiravir may be an alternative therapy due to the absence of such interactions observed so far.

research Investigational medications in the treatment of alopecia

3 citations , February 2005 in “Expert Opinion on Investigational Drugs”

This review discusses investigational treatments for androgenetic and chemotherapy-induced alopecia and reports no new clinical results, highlighting the need for further research.

Dermatological Medications and Local Therapeutics During Pregnancy

research Dermatological medications and local therapeutics

4 citations , September 2014 in “Elsevier eBooks”

This review discusses the safety of dermatological medications used during pregnancy, highlighting that retinoids have strong teratogenic risks and should be used with caution; it reports no new clinical results.

research Medications and hair transplantation

November 2009 in “Cambridge University Press eBooks”

This review discusses the necessity for hair transplant surgeons to be well-versed in both surgical and medical treatments for various forms of alopecia, and it reports no new results.

research Frontal fibrosing alopecia in men: A multicenter study of 39 patients

5 citations , September 2021 in “Journal of The American Academy of Dermatology”

This study found a high prevalence of beard and eyebrow alopecia in male patients with frontal fibrosing alopecia, and suggests a potential link between hormonal imbalances and the condition.

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Community Join

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community Finastride vs Spironolactone, what's more effective? Using together help?

4 upvotes 3 years ago

Using both finasteride and spironolactone together is more effective for hair loss in females, as they have different mechanisms and complement each other. It's important to avoid these medications during pregnancy and choose birth control with anti-androgenic activity.

community Everyone seems to be looking for an antiandrogen as an add on. But what about Estradiol & its derivatives ( excluding the low concentraion alfatradiool ) being used. Anyone has an experience with this ? Anything that won't cause feminization in the process ?

5 upvotes 2 years ago

The conversation discusses using estradiol and its derivatives for hair loss without causing feminization. Users mention alternatives like alfatradiol, topical 17b-Estradiol, and DIM (Diindolylmethane).

community Severe dry eye: finasteride vs dutasteride

8 upvotes 5 years ago

Woman uses antiandrogens for hair thinning prevention, experiences severe dry eye with finasteride. Asks if dutasteride could be better despite potential for worse dry eye.

community Any help with female hair loss?

2 upvotes 11 months ago

A 20-year-old female with PCOS is experiencing hair loss and excessive facial hair. She is using ketoconazole and caffeine shampoos, microneedling, and considering anti-androgens like finasteride, but is cautious about minoxidil due to facial hair concerns.

community 22M, dutasteride + spironolactone miracle, I was losing 400-500 hairs everyday, after starting the drugs I completely stopped shedding and experienced crazy regrowth in just 3-4 months

61 upvotes 1 year ago

A 22-year-old male experienced significant hair regrowth and stopped shedding after using dutasteride and spironolactone for 3-4 months. Spironolactone is discussed as an antiandrogen, typically used for women or transitioning individuals, and not commonly recommended for men due to potential side effects.

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Learn

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learn Ketoconazole

antifungal with some anti-androgenic benefits, often used as a shampoo

learn Spironolactone

powerful topical and oral anti-androgen used mostly by women

learn Bicalutamide

a nonsteroidal anti-androgen, most commonly used orally for women

Can bicalutamide stop DHT from shrinking your hair follicles? Bicalutamide blocks androgens at the receptor rather than lowering DHT, and some dermatologists prescribe it off-label for women with pattern hair loss. The published evidence is retrospective case series and one small pilot study, with no randomized trial; it is a prescription drug that requires liver monitoring and is contraindicated in pregnancy.
Why are some women using bicalutamide to fight hormonal hair loss? Bicalutamide blocks androgens, helping women combat hormonal hair loss effectively.

learn Clascoterone

a novel topical treatment that inhibits DHT on androgen receptors

learn Dutasteride

Heavy duty finasteride that comes with higher risks

learn Finasteride

Is Finasteride unbeatable or are there equally powerful alternatives? Trials report finasteride as the single medication with the strongest measured effect in male androgenetic alopecia, while dutasteride, minoxidil, topical finasteride, PRP, LLLT and microneedling all have supporting studies and are often reported to work better in combination. Finasteride, dutasteride and oral minoxidil are prescription-only, and several of these uses are off-label.

learn Pyrilutamide

Is pyrilutamide a safer alternative to oral antiandrogens like finasteride? Pyrilutamide may be a safer topical alternative to oral antiandrogens like finasteride.

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