Dermatological Alterations Induced by Gynecological Hormonal Imbalances: Acne, Hirsutism, and Alopecia
October 2025
in “
World Journal of Biology Pharmacy and Health Sciences
”
androgens acne hirsutism alopecia polycystic ovary syndrome PCOS insulin resistance hormonal acne combined hormonal contraceptives antiandrogenic medications isotretinoin female pattern hair thinning telogen effluvium estrogen withdrawal thyroid dysfunction trichoscopy hormonal profiling birth control pills Accutane
Studysummary This review highlights the role of sex hormones in skin health, observing that hormonal changes throughout a woman's life can affect skin conditions such as acne and hair loss, with treatments involving hormonal therapies and the importance of a multidisciplinary approach. Our plain-language summary of this paper — not a Tressless recommendation.
Hormonal imbalances, particularly those involving androgens, significantly impact dermatological conditions such as acne, hirsutism, and alopecia in women. Disorders like polycystic ovary syndrome (PCOS) exacerbate these conditions due to elevated androgen levels and insulin resistance. Hormonal acne, often appearing in the lower facial region, can be treated with combined hormonal contraceptives, antiandrogenic medications, or isotretinoin. Excessive hair growth is assessed using standardized scoring systems and managed with hormonal therapies and cosmetic procedures. Hormonal hair loss, including female pattern hair thinning and telogen effluvium, is often linked to estrogen withdrawal or thyroid dysfunction, with diagnosis involving trichoscopy and hormonal profiling. A multidisciplinary approach, integrating dermatological, gynecological, and endocrine care, alongside mental health support, is crucial for improving both physical and emotional outcomes for affected individuals.
