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    Glossary Myofibroblasts

    specialized cells aiding wound healing by contracting and producing collagen

    Myofibroblasts are specialized cells that play a crucial role in wound healing and tissue repair. They have properties of both muscle cells and fibroblasts, allowing them to contract and produce collagen, which helps close wounds and form scar tissue.

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    Research 30 of 1000+

    1. Regeneration of fat cells from myofibroblasts during wound healing Science · 2017 · 408 citations
    2. Dermal Adipocyte Lipolysis and Myofibroblast Conversion Are Required for Efficient Skin Repair Cell Stem Cell · 2020 · 124 citations
    3. Immunophenotypical analyses of myofibroblasts in rat excisional wound healing: possible transdifferentiation of blood vessel pericytes and perifollicular dermal sheath cells into myofibroblasts. PubMed · 2012 · 26 citations
    4. P311 induces the transdifferentiation of epidermal stem cells to myofibroblast-like cells by stimulating transforming growth factor β1 expression Stem Cell Research & Therapy · 2016 · 24 citations
    5. Pharmacological regulation of tissue fibrosis by targeting the mechanical contraction of myofibroblasts Fundamental Research · 2021 · 12 citations
    6. Delayed Collagen Production without Myofibroblast Formation Contributes to Reduced Scarring in Adult Skin Microwounds Journal of Investigative Dermatology · 2023 · 5 citations
    7. 977 The wound healing of fractional photothermolysis mimicks scarless healing with minimal myofibroblast activation Journal of Investigative Dermatology · 2019
    8. Adipocyte-myofibroblast transition as a possible pathophysiological step in androgenetic alopecia Experimental Dermatology · 2017 · 18 citations
    9. Antler stem cell-derived exosomes promote regenerative wound healing via fibroblast-to-myofibroblast transition inhibition Journal of Biological Engineering · 2023 · 17 citations
    10. AB1159 HIGH FAT DIET AND THE ADIPOCYTE TO MYOFIBROBLAST TRANSITION: IMPLICATIONS FOR SYSTEMIC SCLEROSIS CUTANEOUS FIBROSIS 2024
    11. Adipocytic Progenitor Cells Give Rise to Pathogenic Myofibroblasts: Adipocyte-to-Mesenchymal Transition and Its Emerging Role in Fibrosis in Multiple Organs Current Rheumatology Reports · 2020 · 33 citations
    12. Single-cell analysis reveals fibroblast heterogeneity and myeloid-derived adipocyte progenitors in murine skin wounds Nature Communications · 2019 · 301 citations
    13. Fibroblast heterogeneity: implications for human disease Journal of Clinical Investigation · 2018 · 299 citations
    14. Regeneration of Dermis: Scarring and Cells Involved Cells · 2019 · 176 citations
    15. Fibroblasts and wound healing: an update Regenerative Medicine · 2018 · 146 citations
    16. Scarless wound healing: finding the right cells and signals Cell and Tissue Research · 2016 · 132 citations
    17. Human Amniotic Fluid Stem Cell-Derived Exosomes as a Novel Cell-Free Therapy for Cutaneous Regeneration Frontiers in Cell and Developmental Biology · 2021 · 74 citations
    18. Dermal White Adipose Tissue: A Newly Recognized Layer of Skin Innate Defense Journal of Investigative Dermatology · 2019 · 49 citations
    19. Dynamic interplay between IL-1 and WNT pathways in regulating dermal adipocyte lineage cells during skin development and wound regeneration Cell Reports · 2023 · 44 citations
    20. Epigenetic control of skin and hair regeneration after wounding Experimental Dermatology · 2014 · 36 citations
    21. Fibromodulin reduces scar formation in adult cutaneous wounds by eliciting a fetal-like phenotype Signal Transduction and Targeted Therapy · 2017 · 35 citations
    22. Effect of P144® (Anti-TGF-β) in an “In Vivo” Human Hypertrophic Scar Model in Nude Mice PloS one · 2015 · 32 citations
    23. Effect of Chlorhexidine Digluconate in Early Wound Healing of Human Gingival Tissues. A Histological, Immunohistochemical and Biomolecular Analysis Antibiotics · 2021 · 31 citations
    24. Wound healing in development Birth Defects Research · 2012 · 29 citations
    25. Cellular response of keratinocytes to the entry and accumulation of nanoplastic particles Particle and Fibre Toxicology · 2024 · 26 citations
    26. Differential cutaneous wound healing in thermally injured MRL/MPJ mice Wound Repair and Regeneration · 2007 · 26 citations
    27. Repeal and Replace: Adipocyte Regeneration in Wound Repair Cell Stem Cell · 2017 · 22 citations
    28. Tsukushi is involved in the wound healing by regulating the expression of cytokines and growth factors Journal of Cell Communication and Signaling · 2014 · 21 citations
    29. Fibroblasts: Immunomodulatory factors in refractory diabetic wound healing Frontiers in Immunology · 2022 · 20 citations
    30. Palatogenesis and cutaneous repair: A two‐headed coin Developmental Dynamics · 2014 · 20 citations