Wound Healing Mechanism in Mongolian Gerbil Skin
November 2018
in “
Histochemistry and Cell Biology
”
TGF-β1 TGF-β2 TGF-β3 collagen infiltration re-epithelialization hyperplasia hair follicle production collagen deposition RNA sequencing RT-PCR Itga3 Itga5 Acta2 Smad3 CTGF keratin 14 transforming growth factor beta 1 transforming growth factor beta 2 transforming growth factor beta 3 collagen skin healing skin thickening hair growth gene sequencing gene expression analysis integrin alpha 3 integrin alpha 5 alpha smooth muscle actin connective tissue growth factor keratin
Studysummary This study observed that gerbils exhibit a different wound healing mechanism compared to mice, with lower TGF-B1 expression and distinct tissue responses, yet achieve similar healing outcomes.
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