Skin Shedding and Tissue Regeneration in African Spiny Mice (Acomys)

    September 2012 in “ Nature ”
    Ashley W. Seifert, Stephen G. Kiama, Megan G. Seifert … Malcolm Maden
    Studysummary This study reports the first instance of skin autotomy in mammals, specifically in African spiny mice, and suggests they may possess a greater regenerative capacity than previously understood, possibly offering insights for regenerative medicine.
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    Research cited in this study 5

    1. Sox2-Positive Dermal Papilla Cells Specify Hair Follicle Type in Mammalian Epidermis Development · 2009
    2. Wnt-Dependent De Novo Hair Follicle Regeneration in Adult Mouse Skin After Wounding Nature · 2007
    3. BMP Signaling in the Control of Skin Development and Hair Follicle Growth Differentiation · 2004
    4. Multiple Roles for Activated LEF/TCF Transcription Complexes During Hair Follicle Development and Differentiation Development · 1999
    5. Onset of Keratin 17 Expression Coincides with the Definition of Major Epithelial Lineages During Skin Development The Journal of Cell Biology · 1998