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GlossaryCD49f (Integrin alpha-6)

protein aiding cell adhesion and migration, crucial for tissue maintenance

CD49f, also known as Integrin alpha-6 or ITGA6, is a protein found on the surface of certain cells that helps them stick to their surroundings. It plays a crucial role in cell adhesion, migration, and signaling, which are important for processes like wound healing and the maintenance of tissues, including hair follicles.

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signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

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research Wound Healing Mechanism in Mongolian Gerbil Skin

6 citations, November 2018 in “Histochemistry and Cell Biology”

Mongolian gerbils heal wounds differently than mice, with unique protein levels and gene expression that affect skin repair.

research Targeting Integrin Pathways: Mechanisms and Advances in Therapy

54 citations, January 2023 in “Signal Transduction and Targeted Therapy”

New therapies are being developed that target integrin pathways to treat various diseases.

research Laminin 332 Is Indispensable for Homeostatic Epidermal Differentiation Programs

12 citations, May 2021 in “The journal of investigative dermatology/Journal of investigative dermatology”

Laminin 332 is essential for normal skin cell behavior and structure.

research Recently Identified Forms of Epidermolysis Bullosa

39 citations, January 2015 in “Annals of dermatology/Annals of Dermatology”

Three new types of a skin blistering disease were found, caused by specific gene mutations.

research Over-Expression of Thymosin Beta4 Promotes Abnormal Tooth Development and Stimulation of Hair Growth

34 citations, December 2009 in “The International Journal of Developmental Biology”

Too much thymosin beta4 causes weird teeth and more hair growth in mice.

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