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GlossaryMyofibroblasts

specialized cells aiding wound healing by contracting and producing collagen

Myofibroblasts are specialized cells that play a crucial role in wound healing and tissue repair. They have properties of both muscle cells and fibroblasts, allowing them to contract and produce collagen, which helps close wounds and form scar tissue.

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research Regeneration of Fat Cells from Myofibroblasts During Wound Healing

408 citations, January 2017 in “Science”

Some wound-healing cells can turn into fat cells around new hair growth in mice.

research Single-Cell Analysis Reveals Fibroblast Heterogeneity and Myeloid-Derived Adipocyte Progenitors in Murine Skin Wounds

301 citations, February 2019 in “Nature Communications”

The research found that different types of fibroblasts are involved in wound healing and that some blood cells can turn into fat cells during this process.

research Fibroblast Heterogeneity: Implications for Human Disease

299 citations, January 2018 in “Journal of Clinical Investigation”

Different types of fibroblasts play various roles in diseases and healing, and more research on them could improve treatments.

research Regeneration of Dermis: Scarring and Cells Involved

176 citations, June 2019 in “Cells”

Different fibroblasts play key roles in skin healing and scarring.

research Fibroblasts and Wound Healing: An Update

146 citations, July 2018 in “Regenerative Medicine”

Understanding different types of skin cells, especially fibroblasts, can lead to better treatments for wound healing and less scarring.

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